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These studies suggest that the global prevalence of diabetes is rising significantly, with projections indicating increases in both type 1 and type 2 diabetes, particularly in urban and developing regions, and substantial healthcare and social implications.
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Diabetes is a significant global health issue, with its prevalence increasing rapidly over the past few decades. This article synthesizes findings from multiple studies to provide a comprehensive overview of the current state and future projections of diabetes prevalence worldwide.
In 2017, it was estimated that 451 million people aged 18-99 years were living with diabetes globally. This number is projected to rise to 693 million by 2045. Notably, nearly half of these individuals (49.7%) were undiagnosed. Additionally, 374 million people had impaired glucose tolerance (IGT), and approximately 21.3 million live births were affected by hyperglycemia during pregnancy. The global healthcare expenditure on diabetes was around USD 850 billion in 2017, with diabetes-related deaths reaching approximately 5 million in the 20-99 years age range.
In 2015, the global diabetes prevalence was estimated at 415 million people aged 20-79 years, with a projected increase to 642 million by 2040. The majority of these individuals (75%) resided in low- and middle-income countries. The total global health expenditure due to diabetes was estimated at USD 673 billion, with 5 million deaths attributed to the disease.
By 2019, the global diabetes prevalence had risen to 463 million people, with projections indicating an increase to 700 million by 2045. The prevalence was higher in urban areas (10.8%) compared to rural areas (7.2%), and in high-income countries (10.4%) compared to low-income countries (4.0%). Additionally, 50.1% of people with diabetes were unaware of their condition. The global prevalence of IGT was estimated at 374 million in 2019, with projections of 548 million by 2045.
A systematic review and meta-analysis of studies conducted between 1980 and 2015 revealed a significant increase in diabetes prevalence in Brazil. The prevalence rates varied based on the diagnostic method used, with self-reporting showing a prevalence of 5.6%, fasting glucose at 6.6%, and complex diagnosis methods at 11.9%. Over the past three decades, the prevalence of diabetes in Brazil has more than doubled, indicating a growing public health concern.
India has experienced a sharp increase in diabetes prevalence, with rates rising from 2.4% in rural areas and 3.3% in urban areas in 1972 to 15.0% and 19.0%, respectively, by 2015-2019. This trend was observed across both genders and various states, with the highest prevalence in Goa (17.4%) and Tamil Nadu (24.0%) in the latest decade. The urban-rural gap in diabetes prevalence has narrowed, highlighting the need for targeted prevention strategies.
The incidence and prevalence of type 1 diabetes in children and adolescents have also been on the rise. In 2019, the annual incidence of type 1 diabetes was estimated at 98,200 new cases in children under 15 years and 128,900 in those under 20 years. The corresponding prevalence estimates were 600,900 and 1,110,100 existing cases, respectively. These numbers have increased in most regions, reflecting higher incidence rates and improved diagnosis.
The global prevalence of diabetes is expected to continue rising, with estimates indicating a prevalence of 4.4% in 2030, up from 2.8% in 2000. The total number of people with diabetes is projected to increase from 171 million in 2000 to 366 million by 2030. This increase is primarily driven by demographic changes, including an aging population and urbanization in developing countries.
The rising prevalence of diabetes poses significant challenges for healthcare systems worldwide. Increased healthcare expenditure, higher mortality rates, and the need for effective prevention and management strategies are critical issues that need to be addressed. The burden of diabetes is particularly pronounced in low- and middle-income countries, which will experience the greatest increase in cases over the next few decades .
The prevalence of diabetes is increasing globally, with significant implications for public health and healthcare systems. Current estimates and future projections highlight the urgent need for effective prevention, early diagnosis, and management strategies to mitigate the impact of this growing epidemic. Addressing the diabetes burden requires a concerted effort from governments, healthcare providers, and communities worldwide.
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