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These studies suggest that Mediterranean, low-carbohydrate, DASH, and high-protein diets can improve glycemic control and reduce the risk of type 2 diabetes, while high intake of refined grains, sugar-sweetened beverages, and processed meats increases the risk.
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The Mediterranean diet has been extensively studied for its potential benefits in managing and preventing type 2 diabetes. Multiple meta-analyses and systematic reviews have shown that adherence to the Mediterranean diet is associated with a significant reduction in the risk of developing type 2 diabetes. For instance, a meta-analysis of 10 prospective studies involving 136,846 participants found that higher adherence to the Mediterranean diet reduced the risk of developing type 2 diabetes by 23%. Another study highlighted that the Mediterranean diet led to better glycemic control and cardiovascular risk factors compared to lower-fat diets.
The Mediterranean diet's effectiveness can be attributed to its high content of fruits, vegetables, legumes, nuts, whole grains, and olive oil, which are rich in antioxidants, fiber, and healthy fats. These components help improve insulin sensitivity and reduce inflammation, which are crucial in managing diabetes .
Low-carbohydrate diets (LCDs) and very low-carbohydrate diets (VLCDs) have shown promise in the short-term management of type 2 diabetes. A systematic review and meta-analysis of randomized clinical trials found that LCDs achieved higher rates of diabetes remission at six months compared to control diets. Specifically, 57% of participants on LCDs achieved diabetes remission, defined as HbA1c levels below 6.5%. Additionally, these diets led to significant improvements in weight loss, triglycerides, and insulin sensitivity at six months.
However, the benefits of LCDs and VLCDs tend to diminish over time. At 12 months, the improvements in diabetes remission and other health markers were less pronounced, and some participants experienced a decline in quality of life and an increase in low-density lipoprotein cholesterol. This suggests that while LCDs can be effective in the short term, their long-term efficacy and safety require further investigation.
The Dietary Approaches to Stop Hypertension (DASH) and the Alternative Healthy Eating Index (AHEI) diets have also been associated with a reduced risk of type 2 diabetes. A systematic review and meta-analysis found that adherence to the DASH diet was associated with a 19% reduction in diabetes risk, while the AHEI diet was associated with a 21% reduction. These diets emphasize the consumption of fruits, vegetables, whole grains, and lean proteins, which contribute to better glycemic control and reduced inflammation.
Low-glycemic index (GI) and high-protein diets have shown moderate benefits in improving glycemic control and weight loss in people with type 2 diabetes. A systematic review found that these diets led to significant reductions in glycated hemoglobin (HbA1c) levels and body weight compared to control diets. However, the effect sizes were smaller compared to the Mediterranean and low-carbohydrate diets.
In summary, various dietary patterns have been shown to be effective in managing and preventing type 2 diabetes. The Mediterranean diet stands out for its robust evidence base and long-term benefits. Low-carbohydrate diets offer significant short-term improvements but may have limitations in long-term efficacy and safety. Other diets like DASH, AHEI, low-GI, and high-protein diets also provide beneficial effects on glycemic control and cardiovascular risk factors. Future research should focus on the long-term sustainability and overall health impacts of these dietary approaches to provide clearer guidelines for diabetes management.
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