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These studies suggest that systolic blood pressure is more strongly associated with cardiovascular risk and is the primary target for antihypertensive therapy, while diastolic blood pressure is more important in younger individuals and both independently increase the risk of adverse cardiovascular events.
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Systolic blood pressure (SBP) is the pressure exerted on the walls of the arteries when the heart contracts and pumps blood out. It is the higher of the two blood pressure readings and is typically recorded first. Elevated systolic blood pressure has been identified as a significant risk factor for cardiovascular diseases, particularly in older adults. Studies have shown that systolic blood pressure is a stronger predictor of coronary heart disease and other cardiovascular events compared to diastolic blood pressure .
Diastolic blood pressure (DBP), on the other hand, is the pressure in the arteries when the heart is at rest between beats. It is the lower of the two readings. While traditionally considered crucial for cardiovascular risk assessment, recent research indicates that its predictive power may be less significant than that of systolic blood pressure, especially in older populations .
Research comparing the impact of systolic and diastolic blood pressure on cardiovascular outcomes has consistently shown that systolic blood pressure is a more critical factor. For instance, the Framingham study highlighted that systolic blood pressure is a better predictor of coronary heart disease than diastolic pressure, particularly as individuals age. Similarly, a study involving 1.3 million adults found that both systolic and diastolic hypertension independently predicted adverse cardiovascular outcomes, but systolic hypertension had a more substantial effect.
Pulse pressure (PP), the difference between systolic and diastolic blood pressure, has emerged as an important marker of cardiovascular risk. A widened pulse pressure often indicates reduced vascular compliance and is associated with increased cardiovascular risk, particularly in older adults . Studies have shown that pulse pressure is a powerful predictor of cardiovascular events, sometimes even more so than systolic or diastolic pressure alone.
The management of hypertension has evolved with these insights. While both systolic and diastolic pressures are important, the focus has shifted more towards controlling systolic pressure, especially in older adults. This is because elevated systolic pressure is more common and poses a greater risk for cardiovascular events. However, it is also essential to consider pulse pressure and mean arterial pressure (MAP) for a comprehensive assessment of cardiovascular risk.
In summary, while both systolic and diastolic blood pressures are critical for assessing cardiovascular risk, systolic blood pressure is generally a more significant predictor of adverse outcomes. Pulse pressure also plays a crucial role in risk stratification, particularly in older adults. Effective management of hypertension should prioritize controlling systolic pressure while also considering the implications of pulse pressure and mean arterial pressure.
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