Does amoxicillin treat strep throat

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Amoxicillin as a Treatment for Strep Throat

Effectiveness of Amoxicillin in Treating Strep Throat

Amoxicillin is widely recognized as an effective treatment for streptococcal pharyngitis, commonly known as strep throat. Research indicates that a single dose of amoxicillin can significantly reduce the presence of group A Streptococci (GAS) in symptomatic children. In a study involving 111 children with confirmed strep throat, 91% of participants showed no detectable GAS in their throat cultures just 12 to 23 hours after receiving a single dose of amoxicillin (50 mg/kg) . This rapid reduction in bacterial load suggests that amoxicillin is highly effective in treating strep throat.

Safety and Side Effects of Amoxicillin

While amoxicillin is effective, it is not without potential side effects. A case study involving a 22-month-old child treated with amoxicillin/clavulanic acid for strep throat highlights the importance of monitoring for adverse reactions. The child developed a diffuse, erythematous rash after seven days of antibiotic treatment, which was later diagnosed as a drug reaction. This case underscores the need for careful consideration of the risks and benefits of antibiotic therapy, especially in pediatric patients .

Conclusion

Amoxicillin is a highly effective treatment for strep throat, capable of significantly reducing bacterial presence within a short period. However, healthcare providers must remain vigilant for potential side effects and weigh the risks and benefits of treatment on a case-by-case basis.

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Most relevant research papers on this topic

A Reappraisal of the Minimum Duration of Antibiotic Treatment Before Approval of Return to School for Children With Streptococcal Pharyngitis

A single dose of amoxicillin (50 mg/kg) can effectively clear group A Streptococci (GAS) in 91% of children with strep throat, allowing them to return to school as little as 12 hours later.

Non-RCT

2015·

15citations

·Richard H. Schwartz et al.

Taking Chances With Strep Throat.

Discontinuing antibiotics and steroids in children with a rash may be the best course of treatment, considering both the risks and benefits of treatment.

Case Report

2015·

10citations

·Katherine McMurray et al.

Once-Daily Therapy for Streptococcal Pharyngitis With Amoxicillin

Once-daily amoxicillin therapy is as effective as penicillin V therapy given three times a day for treating group A -hemolytic streptococcal pharyngitis in children.

RCTHighly Cited

1999·

109citations

·H. Feder et al.

Different antibiotic treatments for group A streptococcal pharyngitis.

Antibiotics for group A streptococcal pharyngitis show mixed results, with some suggesting that a single antibiotic may be the best choice for treating symptoms and preventing complications.

Systematic ReviewVery Rigorous Journal

2021·

5citations

·M. V. van Driel et al.

Treatment of streptococcal pharyngitis with amoxycillin once a day.

Amoxycillin once daily is as effective as phenoxymethylpenicillin in treating group A beta haemolytic streptococcal pharyngitis.

Highly Cited

1993·

93citations

·P. Shvartzman et al.

The Effect of Amoxicillin-Clavulanate, Cefixime and Azithiromycin on Normal Throat Flora in Children with Group A Streptococcal Pharyngitis

Amoxicillin-clavulanate, azithromycin, and cefixime all effectively preserve normal throat flora in children with group A streptococcal pharyngitis, potentially improving treatment outcomes and reducing the need for antibiotics.

Non-RCT

2003·

5citations

·C. Rush et al.

ONCE-DAILY THERAPY FOR STREPTOCOCCAL PHARYNGITIS WITH AMOXICILLIN VS, INTRAMUSCULAR BENZATHIN PENICILLIN G

Once-daily amoxicillin is as effective as intramuscular benzatine penicillin G for treating group A -hemolytic streptococcal pharyngitis in children.

RCTRigorous Journal

2007·

1citation

·Saeideh Tarvijeslami et al.

Different antibiotic treatments for group A streptococcal pharyngitis.

Antibiotics for group A streptococcal pharyngitis show mixed results in alleviating symptoms, shortening illness duration, and preventing complications, with no clear clear winner.

Systematic Review

2023·

0citations

·Katarina Hedin et al.

Comparative effectiveness of amoxicillin and amoxicillin-clavulanate potassium in acute paranasal sinus infections in children: a double-blind, placebo-controlled trial.

Amoxicillin and amoxicillin-clavulanate potassium are both effective in treating acute maxillary sinusitis in children, with 67% and 64% cure rates respectively.

RCTHighly Cited

1986·

249citations

·E. Wald et al.

Analytical Method Development and Validation of Amoxicillin and Dicloxacillin in API and its Dosage Form by RP-HPLC

The proposed RP-HPLC method is simple, fast, accurate, and precise for estimating Amoxicillin and Dicloxacillin dosage forms in combination capsules, providing accurate and precise results for regular use.

2023·

0citations

·Pramodini K N et al.

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