Does dramamine help with nausea

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Efficacy of Dramamine for Nausea Relief

Dramamine for Postoperative Nausea and Vomiting (PONV)

Effectiveness Compared to Ondansetron
Research indicates that dimenhydrinate (Dramamine) is as effective as ondansetron (Zofran) in preventing postoperative nausea and vomiting (PONV) in patients undergoing elective laparoscopic cholecystectomy. A study involving 108 patients showed no significant difference in the need for rescue antiemetics, postoperative vomiting, or postoperative nausea between the two groups . This suggests that Dramamine is a viable and cost-effective alternative to ondansetron for PONV prevention.

Dramamine for Nausea from Contrast Material

Ineffectiveness in Preventing Nausea from Ioxaglate
A study examining the prophylactic use of dimenhydrinate in patients receiving intra-arterial ioxaglate found that it was ineffective in preventing nausea and vomiting associated with the contrast material. The occurrence of adverse reactions was statistically similar between the dimenhydrinate and placebo groups . This indicates that Dramamine may not be effective for all types of nausea, particularly those induced by contrast materials.

Dramamine for Nausea from Electroshock Therapy and Migraines

Successful Use in Electroshock Therapy and Migraines
Dramamine has shown promising results in treating nausea associated with electroshock therapy and migraines. Patients who experienced nausea or vomiting after electroshock therapy reported significant relief when premedicated with Dramamine . Additionally, it has been successfully used to treat migraine-related nausea, further demonstrating its versatility in managing different types of nausea .

Dramamine for Postanesthetic Nausea and Vomiting

Historical Use and Effectiveness
Historically, Dramamine has been used to control postoperative vomiting with notable success. Early studies reported a reduction in postoperative vomiting by approximately 50% when dimenhydrinate was administered intramuscularly . This finding has been supported by subsequent reports, which highlight its effectiveness in various surgical contexts, including oral surgery .

Conclusion

Dramamine (dimenhydrinate) is effective in preventing and treating nausea and vomiting in several contexts, including postoperative settings and conditions like migraines and electroshock therapy. However, its efficacy may vary depending on the cause of nausea, as it appears less effective for nausea induced by contrast materials. Overall, Dramamine remains a valuable and cost-effective option for managing nausea in various medical scenarios.

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Most relevant research papers on this topic

Antiemetic efficacy of prophylactic dimenhydrinate (Dramamine) vs ondansetron (Zofran)

Prophylactic administration of dimenhydrinate is as effective as ondansetron in preventing postoperative nausea and vomiting in patients undergoing elective laparoscopic cholecystectomy, with potential cost savings of $7.25 million per year.

RCT

2000·

43citations

·Shanu N. Kothari et al.

Dimenhydrinate pretreatment in patients receiving intra-arterial ioxaglate: effect on nausea and vomiting.

Dimenhydrinate is ineffective as a prophylactic agent against nausea and vomiting associated with ioxaglate administration in patients undergoing noncoronary arteriography.

RCTLarge Human Trial

1995·

5citations

·Smith Dc et al.

DRAMAMINE® FOR NAUSEA OF ELECTRIC SHOCK AND MIGRAINE

Dramamine® effectively prevents nausea and vomiting after electroshock therapy, providing a valuable treatment option for patients experiencing these symptoms.

Case Report

1949·

3citations

·E. Kerman

Postanesthetic nausea and vomiting.

Postoperative nausea and vomiting are influenced by physical and metabolic factors, but the patient's psyche has the most impact on the postoperative course.

1952·

33citations

·J. Heiser

Intramuscular use of dimenhydrinate (dramamine) to control postoperative vomiting.

Intramuscular dimenhydrinate (Dramamine) may reduce postoperative vomiting by approximately 50%, but more extensive evaluation is needed.

1955·

11citations

·D. Moore et al.

Treatment of postanesthesia nausea and vomiting.

Dimenhydrinate be used for postanesthesia nausea and vomiting, as it is effective in treating various medical conditions and is well-reported in various medical journals.

1950·

4citations

·C. J. Rudolph et al.

The use of parenteral dramamine to control postoperative vomiting in the office practice of oral surgery: a report of cases.

Parenteral dramamine significantly reduces postoperative vomiting in oral surgery patients, allowing them to remain mentally alert and free from vomiting for hours after the procedure.

Case Report

1954·

1citation

·B. H. Harms

Experimental research on antimotion sickness effects of Chinese medicine "pingandan" pills in cats.

Pingandan 50x and scopolamine 1 mg effectively reduce motion sickness symptoms in cats, while Pingandan 10x and dramamine 25mg show no anti-MS effect.

RCTAnimal Study

1992·

5citations

·J. Pei et al.

Effect of Dramamine on Deiter's nerve cells of rats following vestibular stimulation

Dramamine effectively prevents cytochemical changes in Deiter's nerve cells in response to vestibular stimulation in rats.

1966·

3citations

·K. Sikdar et al.

Radiation sickness and its treatment with dramamine.

Radiation sickness can be effectively treated with dramamine, a drug that reduces nausea and vomiting in patients undergoing therapeutic irradiation.

Observational Study

1951·

1citation

·E. Defeo et al.

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