10 papers analyzed
These studies suggest that the gut microbiome affects diabetes through mechanisms involving specific bacterial strains, metabolic pathways, and immune system functions, with potential treatment strategies including fecal transplantation and probiotics.
18 papers analyzed
The gut microbiome, a complex community of microorganisms residing in the human gastrointestinal tract, has been increasingly recognized for its role in various metabolic diseases, including diabetes. Recent research has focused on understanding how alterations in the gut microbiota composition and its metabolites influence the onset and progression of diabetes, particularly type 2 diabetes (T2D).
Microbiota Composition and Diabetes Association:
Microbiota and Insulin Sensitivity:
Microbial Metabolites and Diabetes Risk:
Gut Microbiota and Inflammation:
Gut Permeability and Diabetes:
Fecal Microbiota Transplantation (FMT):
The gut microbiome plays a significant role in the pathophysiology of diabetes, particularly type 2 diabetes. Alterations in the composition of gut bacteria and their metabolites are associated with insulin resistance, inflammation, and gut permeability, all of which contribute to diabetes development. Therapeutic strategies targeting the gut microbiota, such as probiotics, prebiotics, and fecal microbiota transplantation, hold promise for improving metabolic health and managing diabetes. Further research is needed to fully understand the mechanisms and to develop effective microbiome-based therapies.
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