10 papers analyzed
These studies suggest semaglutide effectively induces significant and sustained weight loss in overweight or obese individuals, with additional benefits such as reduced appetite and improved physical functioning, though it may cause gastrointestinal adverse events.
Semaglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist, has been studied extensively for its potential to induce weight loss in individuals with obesity or overweight, both with and without diabetes. This synthesis aims to present the key findings from multiple research papers on the effects of semaglutide for weight loss.
Significant Weight Loss:
Mechanisms of Action:
Cardiometabolic Benefits:
Safety and Tolerability:
Weight Loss Maintenance:
Semaglutide is an effective pharmacological option for inducing significant weight loss in individuals with obesity or overweight. It works by reducing appetite and food intake, and it provides additional cardiometabolic benefits. While gastrointestinal side effects are common, they are typically manageable. Continuous treatment is essential for sustaining weight loss.
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