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These studies suggest that end-stage chronic heart failure (CHF) patients experience significant daily symptom burden, a wide range of symptoms, anemia, and increased inflammation, highlighting the need for palliative care and advanced therapeutic approaches.
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End-stage congestive heart failure (CHF) is characterized by a high burden of physical and psychological symptoms that significantly impact patients' quality of life. Despite advances in medical therapy, patients with end-stage CHF continue to experience a wide range of distressing symptoms .
Breathlessness is the most prevalent symptom in patients with end-stage CHF, affecting up to 90% of men and 86% of women. Dyspnea, or difficulty breathing, is a hallmark of CHF and is often exacerbated by physical activity .
Fatigue and muscle weakness are also common, contributing to a significant reduction in physical activity and overall functional status. These symptoms are often severe and persistent, impacting daily living and mobility.
Patients frequently experience edema, which is the accumulation of fluid in tissues, leading to swelling, particularly in the lower extremities. This is often accompanied by subcutaneous edema and hydrothorax (fluid in the chest cavity) .
A persistent cough and other respiratory issues are also noted, often due to fluid buildup in the lungs, which can lead to lung edema .
Patients with end-stage CHF often suffer from psychological symptoms such as anxiety and depression. These mood problems are prevalent and can exacerbate the physical symptoms, creating a cycle of worsening health.
Cognitive impairment, including difficulties with memory and concentration, is also reported in patients with severe CHF. This can further complicate the management of the disease and the patient's ability to adhere to treatment regimens.
The combination of physical and psychological symptoms leads to a significantly reduced quality of life. Patients often report a high level of care dependency and a decreased willingness to undergo life-sustaining treatments .
Frequent hospitalizations are common due to the severity of symptoms and complications such as chronic kidney disease (CKD) and anemia, which often coexist with CHF. These hospitalizations further diminish the quality of life and increase the burden on healthcare systems.
End-stage CHF is associated with a wide range of debilitating symptoms that severely impact patients' quality of life. Effective management requires a comprehensive approach that addresses both physical and psychological symptoms. Palliative care programs tailored to the needs of these patients can help improve their quality of life and provide better symptom control .
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