Searched over 200M research papers for "exercise benefits"
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These studies suggest that regular exercise benefits cardiovascular health, cognitive function, mental well-being, and disease prevention.
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Regular exercise is widely recognized for its significant benefits in preventing and managing cardiovascular disease (CVD). Beyond the traditional risk factors such as high blood pressure and cholesterol, exercise induces antiatherogenic adaptations in vascular function and structure, improves cardiac parasympathetic regulation, and provides cardioprotection against ischemia-reperfusion injury . Additionally, exercise promotes a healthy anti-inflammatory environment through the release of muscle-derived myokines, stimulates myocardial regeneration, and supports a healthy gut microbiota, all of which contribute to cardiovascular health.
Exercise has profound effects on cognitive function, particularly in older adults. Systematic reviews and meta-analyses have shown that exercise significantly improves both physical and cognitive functions, with a positive correlation between the improvements in these two areas. Exercise increases levels of brain-derived neurotrophic factor (BDNF) and other growth factors, stimulates neurogenesis, and enhances brain plasticity, which collectively improve learning and mental performance. These benefits are crucial for aging populations, as they help maintain cognitive health and delay the onset of cognitive decline and diseases such as Alzheimer's.
Exercise is also beneficial for mental health, helping to alleviate symptoms of depression, stress, and anxiety. It enhances affective experience by increasing high-arousal positive affect and reducing low-arousal positive affect, regardless of age. Yoga, a form of exercise, has been found to be as effective as or even superior to traditional exercise in improving various health-related outcomes, particularly in regulating the hypothalamic-pituitary-adrenal (HPA) axis and the sympathetic nervous system (SNS).
Regular physical activity is essential for healthy aging, as it helps maintain physical function and reduces the risk of chronic diseases such as osteoporosis, diabetes, and obesity. Exercise keeps joints, tendons, and ligaments flexible, making movement easier and reducing the discomfort associated with conditions like osteoarthritis. It also increases energy and endurance, improves sleep quality, and helps maintain a healthy weight by boosting metabolism.
The molecular mechanisms underlying the benefits of exercise are complex and involve polygenic interactions within cells, tissues, and organs. Exercise improves cardiovascular fitness, enhances insulin sensitivity, and promotes favorable changes in plasma lipoprotein profiles. It also mobilizes gene expression profiles that benefit brain plasticity processes and increases the availability of vasodilatory mediators such as nitric oxide, which suppresses atherogenesis .
In summary, the benefits of regular exercise are extensive and multifaceted, impacting cardiovascular health, cognitive function, mental well-being, and overall physical health. Exercise promotes a holistic improvement in health by influencing various physiological systems and molecular pathways. Therefore, incorporating regular physical activity into daily routines is essential for maintaining and enhancing overall health and well-being.
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