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These studies suggest that soluble dietary fibers, particularly from sources like oat, psyllium, pectin, and Plantago ovata husk, can effectively lower total and LDL cholesterol levels, contributing to dietary therapy for lowering cholesterol.
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Dietary fiber, particularly soluble fiber, has been extensively studied for its potential to lower cholesterol levels and reduce the risk of cardiovascular disease (CVD). This article synthesizes findings from multiple research studies to provide a comprehensive overview of how dietary fiber impacts cholesterol levels.
A meta-analysis of 67 controlled trials quantified the cholesterol-lowering effects of various soluble fibers, including pectin, oat bran, guar gum, and psyllium. The study found that consuming 2-10 grams per day of soluble fiber resulted in small but significant decreases in total cholesterol and LDL cholesterol. Specifically, each gram of soluble fiber was associated with a reduction of 0.045 mmol/L in total cholesterol and 0.057 mmol/L in LDL cholesterol. These effects were consistent across different types of soluble fiber, indicating that increasing soluble fiber intake can contribute to lowering cholesterol levels.
A study evaluating the long-term effects of a dietary supplement containing both water-soluble and non-water-soluble fibers found significant reductions in LDL cholesterol and total cholesterol over a 51-week period. The fiber supplement led to a 12.1% decrease in LDL cholesterol and an 8.5% decrease in total cholesterol without affecting HDL cholesterol or triglycerides. This suggests that fiber supplements can provide sustained cholesterol-lowering benefits.
Research has shown that different sources of dietary fiber can have varying impacts on cholesterol levels. For instance, Plantago ovata husk (Po-husk) was found to reduce LDL cholesterol by 6%, total cholesterol by 6%, and triglycerides by 21.6% in hypercholesterolemic patients. Similarly, flaxseed dietary fibers, particularly when consumed as a drink, significantly lowered total and LDL cholesterol by 12% and 15%, respectively.
The cholesterol-lowering effects of soluble fiber are more pronounced compared to insoluble fiber. A study involving high intakes of foods rich in soluble fiber demonstrated a greater reduction in total and LDL cholesterol levels compared to insoluble fiber. The study also found that the loss of fecal bile acids was significantly higher during the soluble-fiber period, suggesting that increased bile acid excretion may be a mechanism through which soluble fiber lowers cholesterol.
Foods rich in soluble fiber, such as oats, barley, legumes, and certain fruits, have been shown to decrease LDL cholesterol levels. These foods not only provide soluble fiber but also contain other beneficial phytochemicals that may enhance their cholesterol-lowering effects .
A systematic review of randomized controlled trials (RCTs) concluded that increased fiber intake is associated with significant reductions in total and LDL cholesterol, as well as diastolic blood pressure. However, the review highlighted the need for longer-term studies to better understand the effects of different types of fiber and their administration methods on CVD outcomes.
Incorporating fiber-rich foods into the diet can be an effective strategy for lowering cholesterol. For example, consuming three servings of oatmeal daily can decrease total and LDL cholesterol by approximately 0.13 mmol/L. Additionally, fiber supplements can be a convenient option for individuals who may struggle to meet their fiber needs through diet alone.
Increasing dietary fiber intake, particularly soluble fiber, can significantly lower total and LDL cholesterol levels, contributing to the primary prevention of cardiovascular disease. While the effects are modest, they are consistent across various types of soluble fiber and can be sustained over the long term. Future research should focus on the long-term effects of different fiber types and their potential synergies with other dietary components.
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