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These studies suggest that soluble dietary fibers, particularly from sources like oat, psyllium, pectin, and Plantago ovata husk, can effectively lower total and LDL cholesterol levels, supporting their use in dietary therapy for managing cholesterol.
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Dietary fiber, particularly soluble fiber, has been extensively studied for its potential to lower cholesterol levels. High cholesterol is a significant risk factor for cardiovascular diseases, and managing it through diet is a crucial strategy. This article synthesizes findings from multiple studies to provide a comprehensive overview of how dietary fiber can help lower cholesterol levels.
A meta-analysis of 67 controlled trials quantified the cholesterol-lowering effects of various soluble fibers, including pectin, oat bran, guar gum, and psyllium. The study found that consuming 2-10 grams per day of soluble fiber resulted in small but significant reductions in total cholesterol and LDL cholesterol. Specifically, each gram of soluble fiber reduced total cholesterol by 0.045 mmol/L and LDL cholesterol by 0.057 mmol/L. This effect was consistent across different types of soluble fiber, indicating that increasing soluble fiber intake can contribute to lowering cholesterol levels.
A randomized trial evaluated the effects of Plantago ovata (Po) husk on cardiovascular disease risk biomarkers. The study found that consuming 14 grams per day of Po-husk significantly reduced LDL cholesterol by 6%, total cholesterol by 6%, and triglycerides by 21.6%. Additionally, it lowered oxidized LDL, insulin levels, and systolic blood pressure, making it beneficial for individuals with multiple cardiovascular risk factors.
Research on C57BL/6 mice compared the effects of various dietary fibers, including soybean fiber, rice bran, oat bran, barley bran, and mixed bran. The study found that soybean fiber and rice bran significantly lowered total blood cholesterol compared to a fiber-free diet. However, oat bran, mixed bran, and barley bran did not show significant effects on blood cholesterol levels.
A study on soluble-fiber breakfast cereals found that incorporating pectin-enriched or psyllium-enriched cereals into the diet of hypercholesterolemic patients led to significant reductions in total and LDL cholesterol. The psyllium-enriched cereal group experienced a 5.9% reduction in total cholesterol and a 5.7% reduction in LDL cholesterol, supporting the use of soluble-fiber cereals as part of a cholesterol-lowering diet.
Flaxseed dietary fibers, particularly in the form of a flax drink, were shown to lower fasting total cholesterol by 12% and LDL cholesterol by 15%. The study also noted increased fecal fat and energy excretion, suggesting that the food matrix and processing of flaxseed fibers play a role in their effectiveness.
A study involving very high intakes of soluble fiber in a diet low in saturated fat and cholesterol found that such a diet could further lower blood cholesterol levels. The study reported a 4.9% reduction in total cholesterol and a 4.8% reduction in LDL cholesterol, even when saturated fat and cholesterol intake were already minimized.
Incorporating high-fiber foods into a Mediterranean-Western diet also showed significant cholesterol-lowering effects. Subjects consuming a low-fat, high-fiber diet experienced a 14.2% reduction in total cholesterol and a 17.6% reduction in LDL cholesterol, highlighting the benefits of combining fiber with a heart-healthy diet.
The evidence strongly supports the role of dietary fiber, particularly soluble fiber, in lowering cholesterol levels. Various sources of soluble fiber, including specific fiber-rich foods and high-fiber diets, have been shown to reduce total and LDL cholesterol. While the effects may be modest, incorporating soluble fiber into the diet can be a valuable component of a comprehensive strategy to manage cholesterol and reduce cardiovascular risk.
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