Gabapentin side effects in elderly woman
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Gabapentin Side Effects in Elderly Women
Common Side Effects of Gabapentin in Elderly Women
Gabapentin, an anticonvulsant medication, is frequently prescribed for conditions such as neuropathic pain, seizures, and bipolar disorder. While it is generally well-tolerated, elderly women may experience several side effects. Common adverse effects include somnolence, dizziness, ataxia, and peripheral edema .
Alopecia as a Rare Side Effect
Alopecia, or hair loss, is a rare but possible side effect of gabapentin. Although previously reported in younger individuals, a case study has documented alopecia in an elderly female patient attributed to gabapentin use . This highlights the need for healthcare providers to be vigilant about less common side effects in older populations.
Increased Risk of Delirium and Other In-Hospital Adverse Events
Perioperative use of gabapentin in elderly patients undergoing major surgery has been associated with an increased risk of several adverse clinical events. These include delirium, new antipsychotic use, and pneumonia. Specifically, the risk of delirium was significantly higher in patients with a high comorbidity burden and those with chronic kidney disease . This suggests that careful risk-benefit assessment is crucial when prescribing gabapentin for perioperative pain management in older adults.
Stuttering Induced by Gabapentin
Stuttering is another rare side effect of gabapentin, as evidenced by a case involving a 58-year-old woman who developed stuttering after starting gabapentin for seizure control. The stuttering resolved upon discontinuation of the medication, indicating a direct link between gabapentin use and this speech disorder .
Anorgasmia in Older Patients
Anorgasmia, or the inability to achieve orgasm, has been reported in older patients taking gabapentin. This side effect appears to be dose-dependent and more common than previously thought. In a small case series, three out of eleven patients over the age of 50 experienced anorgasmia, which resolved upon reducing or discontinuing the medication . This underscores the importance of discussing sexual health with older patients on gabapentin.
Conclusion
While gabapentin is effective for various conditions, it is associated with several side effects in elderly women, including common issues like somnolence and dizziness, as well as rarer effects such as alopecia, delirium, stuttering, and anorgasmia. Healthcare providers should carefully monitor elderly patients on gabapentin and consider these potential adverse effects when making treatment decisions.
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