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Some studies suggest heart failure is a leading cause of death, while other studies indicate it is overestimated in cause-of-death statistics.
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Heart failure (HF) is a condition where the heart is unable to pump sufficient blood to meet the body's needs. This condition often leads to the heart compensating by dilating, becoming hypertrophic, or beating faster. HF is a significant health issue globally, particularly among individuals over 65 years old, where it is the most common cause of hospitalization. Despite advancements in medical treatments, HF remains a leading cause of death in many countries.
Cardiovascular disease, including HF, is the leading cause of death in the Western world, surpassing even cancer in mortality rates. The prevalence of HF is increasing due to the aging population, although its incidence has stabilized. HF patients often have a worse survival rate compared to cancer patients, highlighting the severe prognosis associated with this condition.
Heart failure is frequently listed among the top ten leading causes of death in mortality statistics. However, there is a notable overestimation in these statistics due to the way death certificates are completed and interpreted. When physicians list HF on death certificates, it is often considered the underlying cause of death in 21.4% of cases, but in statistical coding, this figure rises to 39.2%. This discrepancy is due to incorrect completion of death certificates and differing opinions on the role of HF as a cause of death.
The causes of death in HF patients are diverse and depend on the type of HF. Patients with preserved ejection fraction (EF) often die from non-cardiovascular diseases, while those with reduced EF are more likely to die from coronary heart disease. Over time, the proportion of cardiovascular deaths in patients with preserved EF has decreased, while it has remained relatively stable in those with reduced EF. Factors such as advanced age, male sex, diabetes, smoking, and kidney disease increase the risk of both all-cause and cardiovascular deaths in HF patients.
In patients with end-stage renal disease (ESRD), cardiovascular disease, including HF, is the leading cause of mortality, accounting for 40% of all deaths. Similarly, in adults with congenital heart disease (ACHD), HF is a leading cause of death, with a significant proportion of deaths being CHD-related.
The socioeconomic burden of HF is substantial, with HF being the most common reason for hospitalization in the elderly. Hospitalization for HF is often followed by a poor prognosis and contributes significantly to healthcare costs. Improving the management of HF patients in hospitals, enhancing adherence to treatment guidelines, and addressing comorbid conditions can help reduce the medical and socioeconomic burden of HF.
Heart failure remains a leading cause of death worldwide, with significant implications for healthcare systems and patient outcomes. While advancements in treatment have been made, the high mortality rate and socioeconomic burden associated with HF underscore the need for continued research and improved management strategies. Addressing the overestimation in mortality statistics and focusing on comprehensive care for HF patients can help mitigate the impact of this pervasive condition.
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