Searched over 200M research papers
10 papers analyzed
These studies suggest hiccups are caused by disruptions in the hiccup reflex arc, gastrointestinal reflexes, neurogenic dysfunctions, and can be triggered by factors such as rapid oesophageal distension, drug reactions, and rare medical conditions.
19 papers analyzed
Hiccups are involuntary contractions of the diaphragm and intercostal muscles, followed by the sudden closure of the glottis, producing a characteristic "hic" sound. While often transient and harmless, hiccups can sometimes become persistent or intractable, causing significant discomfort and requiring medical attention.
Hiccups are typically a benign and self-limiting condition caused by a reflex arc involving the diaphragm and intercostal muscles. However, persistent and intractable hiccups can result from various underlying conditions, including gastrointestinal issues, CNS disorders, and certain medications. Effective treatment often requires identifying and addressing the underlying cause, with both pharmacological and non-pharmacological options available.
Most relevant research papers on this topic