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These studies suggest there are 4 stages of kidney failure.
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Chronic kidney disease (CKD) is a progressive condition characterized by the gradual loss of kidney function over time. The severity of CKD is classified into five distinct stages, with kidney failure being the most severe stage, also known as stage 5 or end-stage renal disease (ESRD) .
In stage 1, there is mild kidney damage with a normal or high glomerular filtration rate (GFR) of 90 mL/min or higher. Despite the normal GFR, there are often signs of kidney damage, such as protein in the urine (proteinuria).
Stage 2 is characterized by a mild reduction in kidney function, with a GFR between 60 and 89 mL/min. Similar to stage 1, there may be evidence of kidney damage, such as proteinuria or abnormalities in blood or urine tests.
Stage 3 is divided into two sub-stages:
Patients in stage 3 often start to experience symptoms such as fatigue, swelling, and changes in urination patterns. This stage is critical for early intervention to slow the progression of the disease .
In stage 4, the GFR drops to between 15 and 29 mL/min. This stage is marked by a significant decline in kidney function, and patients often experience more severe symptoms, including anemia, bone disease, and cardiovascular complications. Preparation for potential dialysis or kidney transplantation typically begins in this stage .
Stage 5, also known as end-stage renal disease (ESRD), occurs when the GFR falls below 15 mL/min. At this stage, the kidneys can no longer maintain the body's balance of fluids, electrolytes, and waste products. Patients require dialysis or a kidney transplant to survive .
Early detection and management of CKD are crucial to slowing the progression of the disease and improving patient outcomes. Regular monitoring of kidney function through blood and urine tests can help identify CKD in its early stages, allowing for timely intervention .
Chronic kidney disease progresses through five stages, with each stage representing a further decline in kidney function. Understanding these stages is essential for the effective management and treatment of CKD, ultimately aiming to delay the onset of kidney failure and improve the quality of life for patients. Early detection and proactive management are key to mitigating the adverse outcomes associated with this condition.
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