Januvia effects on body weight
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Sitagliptin (Januvia) and Body Weight in Type 2 Diabetes
Neutral Effect of Januvia on Body Weight
Clinical studies consistently show that sitagliptin (Januvia) does not cause weight gain in patients with type 2 diabetes. Multiple trials and reviews have found that sitagliptin has a neutral effect on body weight, meaning it neither increases nor decreases weight significantly when used alone or in combination with other diabetes medications 12. This is an important distinction compared to some other diabetes treatments, which are known to cause weight gain.
Comparison with Other Diabetes Medications
Unlike some antihyperglycemic drugs that can lead to weight gain, sitagliptin stands out for its weight neutrality. This makes it a preferred option for patients who are concerned about weight management as part of their diabetes care 12. The low risk of hypoglycemia and the absence of weight gain are key benefits highlighted in clinical experience with sitagliptin.
Effects in Combination Therapies
When sitagliptin is used in combination with other treatments, such as metformin, the neutral effect on body weight remains consistent. Studies have not shown any significant increase in body weight when sitagliptin is added to existing diabetes regimens 12.
Conclusion
In summary, Januvia (sitagliptin) is effective for glycemic control in type 2 diabetes and is generally well tolerated, with a neutral effect on body weight. This makes it a suitable choice for patients who want to avoid weight gain while managing their diabetes 12.
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