Lack of b12 and hair loss
Pro Research Analysisby 
Searched over 200M research papers
Vitamin B12 Deficiency and Hair Loss: An Overview
Introduction to Vitamin B12 and Hair Health
Vitamin B12, also known as cobalamin, is a crucial water-soluble vitamin that plays a significant role in various bodily functions, including DNA synthesis, red blood cell formation, and neurological function. Its deficiency can lead to several health issues, including hair loss. This article explores the relationship between vitamin B12 deficiency and hair loss, drawing insights from multiple research studies.
Vitamin B12 Deficiency and Diffuse Hair Loss
Diffuse hair loss, characterized by a general thinning of hair across the scalp, is a common condition affecting many individuals, particularly women. Research indicates that vitamin B12 deficiency is a contributing factor to this type of hair loss. A study involving pregnant women found that those experiencing severe hair loss during their last two trimesters had significantly lower levels of vitamin B12, among other nutrients, compared to non-pregnant women. This suggests that maintaining adequate vitamin B12 levels is essential for preventing diffuse hair loss, especially during pregnancy.
Chronic Telogen Effluvium and Vitamin B12
Chronic telogen effluvium (CTE) is another form of diffuse hair loss, characterized by the abrupt onset of hair shedding lasting more than six months. Studies have shown a significant association between vitamin B12 deficiency and CTE. One case-control study found that 60% of patients with CTE had vitamin B12 deficiency, compared to only 26% in the control group. Another study corroborated these findings, reporting low vitamin B12 levels in approximately one-third of women with CTE. These findings highlight the importance of monitoring and managing vitamin B12 levels in individuals with chronic telogen effluvium.
Reversible Hair Changes Due to Vitamin B12 Deficiency
Vitamin B12 deficiency can also lead to reversible changes in hair pigmentation and texture. For instance, a case study reported a child with hypopigmented, sparse, and lusterless hair due to vitamin B12 deficiency. After receiving vitamin B12 supplementation, the child's hair returned to a healthy, dark state. Similarly, another case documented reversible premature graying of hair in a patient with vitamin B12 deficiency caused by pernicious anemia. The patient's hair color normalized following treatment with intramuscular cyanocobalamin. These cases underscore the potential for hair recovery with appropriate vitamin B12 supplementation.
Nutritional Deficiencies and Hair Loss Post-Surgery
Hair loss is a common complication following metabolic and bariatric surgery (MBS), often linked to nutritional deficiencies. A systematic review and meta-analysis found that while low levels of zinc, folic acid, and ferritin were significantly associated with hair loss post-MBS, vitamin B12 levels did not show a significant correlation. This suggests that while vitamin B12 is crucial for overall health, other micronutrients may play a more direct role in hair loss following such surgeries.
Conclusion
Vitamin B12 deficiency is a significant factor contributing to various forms of hair loss, including diffuse hair loss and chronic telogen effluvium. Ensuring adequate intake of vitamin B12 through diet or supplementation can help prevent and potentially reverse hair loss associated with its deficiency. However, it is also important to consider other nutritional factors and underlying health conditions that may contribute to hair loss. Regular screening and timely intervention can aid in maintaining healthy hair and overall well-being.
Sources and full results
Most relevant research papers on this topic