Mangosteen juice health benefits
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Mangosteen Juice Antioxidant and Anti-Inflammatory Benefits
Research shows that mangosteen juice can increase antioxidant capacity and reduce inflammation in the body. In a clinical trial, healthy adults who consumed a mangosteen-based drink for 30 days had a 15% higher antioxidant capacity in their blood compared to those who took a placebo. Additionally, their C-reactive protein (CRP), a marker of inflammation, dropped by 46%, while the placebo group saw no significant change. Importantly, no negative effects on liver, kidney, or immune function were observed during the study period, suggesting that mangosteen juice is safe for regular consumption in healthy adults .
Another study in obese individuals found that high doses of a proprietary mangosteen juice blend significantly reduced CRP levels compared to placebo after 8 weeks. There was also a trend toward lower body mass index (BMI) in the juice groups, and no side effects were reported . These findings support the anti-inflammatory and potential weight management benefits of mangosteen juice.
Bioactive Compounds and Mechanisms of Action
Mangosteen juice is rich in xanthones, a group of polyphenols with strong antioxidant, anti-inflammatory, anti-cancer, anti-viral, and anti-diabetic properties. These compounds are believed to be responsible for many of the health benefits associated with mangosteen juice, including support for heart health, blood sugar regulation, and protection against chronic diseases 27.
Studies confirm that xanthones from mangosteen juice are absorbed by the body, especially when consumed with a high-fat meal. However, the release of xanthones from the fruit’s pericarp (outer layer) during digestion may be limited, which could affect how much the body can use .
Blood Sugar and Diabetes Management
Mangosteen peel juice, which is high in xanthones and flavonoids, has been shown to help stabilize blood sugar levels in people with diabetes. In a small study, diabetic patients who consumed mangosteen peel juice experienced a significant reduction in blood sugar levels, suggesting its potential as a natural supplement for diabetes management . Other reviews also highlight mangosteen’s hypoglycemic (blood sugar lowering) effects .
Additional Health Benefits and Functional Food Potential
Mangosteen juice and extracts have demonstrated antibacterial, antiviral, antitumor, and neuroprotective effects. They may help lower LDL cholesterol, reduce blood pressure, prevent atherosclerosis, and protect the heart. There is also evidence suggesting benefits for conditions like Alzheimer’s and Parkinson’s disease, chronic pain, and menopausal symptoms 27.
Innovative approaches, such as fermenting mangosteen pericarp extract juice with probiotics, have been shown to further enhance its antioxidant properties and create functional drinks with added health benefits . Mangosteen peel juice is also rich in nutrients like fiber and protein, making it a valuable and economical ingredient for health beverages .
Safety Considerations
Most studies report that mangosteen juice is safe for regular consumption, with no significant side effects on liver, kidney, or immune function in healthy adults 14. However, there has been a rare case of severe lactic acidosis associated with mangosteen juice use, indicating that caution may be needed for individuals with underlying health conditions .
Conclusion
Mangosteen juice offers a range of health benefits, including increased antioxidant capacity, reduced inflammation, improved blood sugar control, and potential protection against chronic diseases. These effects are largely attributed to its rich content of xanthones and other bioactive compounds. While generally safe for most people, those with health concerns should consult a healthcare provider before using mangosteen juice as a supplement. Further research with larger populations is needed to confirm and expand on these promising findings.
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