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These studies suggest that various natural remedies, including Reishi, diterpenes, traditional medicinal plants, ginseng, fenugreek, ginkgo biloba, herbal acupoint therapy, Ruscus aculeatus, aromatic plants, Cordyceps sinensis, and Nangapiry, show potential in treating hypotension and hypertension with varying mechanisms and safety profiles.
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Hypotension, or low blood pressure, can lead to symptoms such as dizziness, fainting, and in severe cases, shock. While conventional treatments are available, they often come with side effects, prompting interest in natural remedies. This article explores various natural treatments for hypotension, drawing on recent research findings.
Reishi mushroom, known scientifically as Ganoderma lucidum, has shown promise as a natural remedy for hypotension. In a study involving hypertensive rats, Reishi extract was administered intragastrically, resulting in a significant reduction in blood pressure comparable to the effects of losartan, a standard antihypertensive drug. Additionally, Reishi increased cerebral blood flow and altered cerebral cortex metabolic patterns, suggesting potential nootropic benefits.
Diterpenes, naturally occurring compounds found in plants, have been identified for their hypotensive properties. Forskolin and stevioside, in particular, exhibit vasorelaxant actions and inhibit vascular contractility through different mechanisms. These compounds have been evaluated for their potential as antihypertensive agents, showing promising results in reducing blood pressure.
Several traditional medicinal plants (TMPs) and natural products have been recognized for their vasodilatory and hypotensive activities. Plants from families such as Compositae, Lamiaceae, and Orchidaceae, and compounds like flavonoids, phenolic acids, and alkaloids, have shown potential in activating endothelial nitric oxide synthase (eNOS) and blocking calcium channels, thereby promoting vasodilation and reducing blood pressure.
Herbal acupoint therapy (HAT) has been studied for its efficacy in treating intradialytic hypotension (IDH) in hemodialysis patients. A randomized, placebo-controlled trial demonstrated that HAT significantly reduced the frequency of IDH episodes, required fewer nursing interventions, and improved fatigue levels post-dialysis. This suggests that HAT is a safe and effective treatment for IDH.
Ruscus aculeatus, commonly known as butcher's broom, has been proposed as a treatment for orthostatic hypotension (OH). This phytotherapeutic agent possesses vasoconstrictive and venotonic properties, making it suitable for managing blood pooling in the limbs and improving venous tone. Unlike many pharmacological treatments, Ruscus aculeatus does not cause supine hypertension and is considered safe and inexpensive.
Aromatic plants such as Lavandula angustifolia, Pelargonium graveolens, Origanum majorana, and Ocimum basilicum have been evaluated for their hypotensive effects. An experiment involving 38 volunteers with mild hypertension showed that natural incense from these plants significantly reduced both systolic and diastolic blood pressure, along with improving mental outlook.
Cordyceps sinensis, a traditional Chinese herb, has demonstrated hypotensive and vasorelaxant activities. In studies with anesthetized rats, Cordyceps sinensis extract significantly reduced mean arterial pressure in a dose-dependent manner. The vasorelaxation effect is mediated by the endothelium, likely through the release of nitric oxide and endothelium-derived hyperpolarizing factor.
Natural remedies for hypotension, including Reishi mushroom, diterpenes, traditional medicinal plants, herbal acupoint therapy, Ruscus aculeatus, aromatic plants, and Cordyceps sinensis, offer promising alternatives to conventional treatments. These natural agents not only help manage blood pressure but also come with fewer side effects, making them attractive options for long-term use. Further research and clinical trials are necessary to fully understand their efficacy and safety profiles.
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