Natural supplements to lower cholesterol
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Natural Supplements to Lower Cholesterol
Plant Sterols and Stanols: Effective Cholesterol-Lowering Agents
Plant sterols and stanols are well-documented for their cholesterol-lowering properties. Studies have shown that these compounds can significantly reduce total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) levels. For instance, the DESCO study demonstrated that a daily supplement containing 2.5 g of phytosterols led to a significant reduction in TC and LDL-C levels in individuals with polygenic hypercholesterolemia, especially when combined with a Mediterranean diet . Another study confirmed that unesterified plant sterols and stanols, when consumed at a dosage of 1.8 g/day, effectively lowered LDL-C by 11.3% to 16.0% in hypercholesterolemic individuals .
Red Yeast Rice, Policosanols, and Artichoke Leaf Extracts: Combined Natural Supplement
A combined natural supplement (NCLS) containing red yeast rice, policosanols, and artichoke leaf extracts has been shown to reduce LDL-C by 14.3% over 16 weeks in subjects with moderate hypercholesterolemia. This supplement also lowered total cholesterol and apolipoprotein B100 without affecting safety parameters, making it a viable option for cholesterol management .
Vitamin C: A Potent Antioxidant for Cholesterol Reduction
Vitamin C supplementation has been found to significantly decrease serum LDL-C and triglyceride levels. A meta-analysis of 13 randomized controlled trials revealed that a daily intake of at least 500 mg of vitamin C for a minimum of four weeks resulted in a reduction of LDL-C by 7.9 mg/dL and triglycerides by 20.1 mg/dL .
Oat β-Glucan and Phytosterols: Synergistic Effects
Combining high molecular weight oat β-glucan (OBG) with phytosterols (PS) has shown enhanced lipid-lowering effects. A study found that this combination significantly reduced TC and LDL-C levels more than either component alone. The PS-OBG combination lowered TC by 11.5% and LDL-C by 13.9%, indicating a synergistic effect that optimizes heart health .
Capsaicinoids: Novel Cholesterol-Lowering Approach
Capsaicinoids, found in chili peppers, have been identified as effective in lowering serum total cholesterol and LDL-C levels. A meta-analysis of controlled human trials concluded that capsaicinoid supplementation significantly reduced total cholesterol and LDL-C, providing a novel dietary intervention for cholesterol management .
Omega-3 Fatty Acids: EPA-Rich Extracts
Omega-3 fatty acids, particularly eicosapentaenoic acid (EPA), have been shown to decrease cholesterol levels. A study involving an EPA-rich extract from the microalga Nannochloropsis demonstrated a significant reduction in very-low-density lipoprotein cholesterol (VLDL) and total cholesterol without increasing LDL-C, making it a beneficial supplement for cholesterol management .
Ginger: Traditional Remedy with Modern Evidence
Ginger supplementation has been found to reduce triglycerides and LDL-C levels. A systematic review and meta-analysis of clinical trials indicated that ginger, especially at doses of 2 g/day or less, significantly lowered triglycerides and total cholesterol, although its effect on LDL-C was less pronounced .
Conclusion
Natural supplements such as plant sterols, red yeast rice, vitamin C, oat β-glucan, capsaicinoids, omega-3 fatty acids, and ginger have shown significant potential in lowering cholesterol levels. These supplements can be effective either alone or in combination, providing various options for individuals seeking to manage their cholesterol through natural means. Always consult with a healthcare provider before starting any new supplement regimen.
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