Nausea on lexapro

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Nausea as a Side Effect of Lexapro (Escitalopram)

Introduction to Lexapro and Its Uses

Lexapro, also known as escitalopram, is a selective serotonin reuptake inhibitor (SSRI) commonly prescribed for the treatment of major depressive disorder and generalized anxiety disorder. It works by increasing the levels of serotonin in the brain, which can help improve mood and reduce anxiety .

Common Adverse Effects of Lexapro

While Lexapro is effective in treating depression and anxiety, it is associated with several adverse effects. Among these, nausea is one of the most frequently reported side effects. Clinical trials have shown that nausea occurs in approximately 18% of patients taking Lexapro, compared to 8% of those taking a placebo . This makes nausea one of the most common gastrointestinal complaints among Lexapro users.

Incidence of Nausea in Clinical Trials

In a multicenter double-blinded randomized controlled trial comparing generic escitalopram to Lexapro, nausea was reported by 10.8% of patients in the Lexapro group . This aligns with other studies that have consistently identified nausea as a prevalent side effect of Lexapro treatment .

Dose Dependency of Nausea

The incidence of nausea appears to be dose-dependent. Higher doses of Lexapro (20 mg/day) are associated with a greater likelihood of experiencing nausea compared to lower doses (10 mg/day) and placebo . This suggests that patients on higher doses of Lexapro may need closer monitoring for gastrointestinal side effects.

Managing Nausea in Patients on Lexapro

Given the high incidence of nausea, healthcare providers often recommend several strategies to manage this side effect. These may include taking the medication with food, starting at a lower dose and gradually increasing it, or using anti-nausea medications as needed. It is crucial for patients to communicate any adverse effects to their healthcare provider to adjust the treatment plan accordingly.

Conclusion

Nausea is a common side effect of Lexapro, affecting a significant proportion of patients. Understanding the prevalence and management strategies for this side effect can help improve patient adherence to the medication and overall treatment outcomes. Healthcare providers should monitor patients closely, especially those on higher doses, to mitigate the impact of nausea and ensure effective treatment of depression and anxiety disorders.

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