Obsessive compulsive pd
Pro Research Analysisby 
Searched over 200M research papers
Obsessive-Compulsive Personality Disorder (OCPD) and Parkinson's Disease (PD)
Introduction to Obsessive-Compulsive Personality Disorder (OCPD) in Parkinson's Disease (PD)
Obsessive-Compulsive Personality Disorder (OCPD) is characterized by a chronic preoccupation with rules, orderliness, and control. Recent studies have explored the prevalence and impact of OCPD and related obsessive-compulsive symptoms (OCS) in patients with Parkinson's Disease (PD), a neurodegenerative disorder primarily affecting motor function but also linked to various psychiatric conditions.
Prevalence of Obsessive-Compulsive Symptoms in PD
Research indicates a significant presence of obsessive-compulsive symptoms in PD patients. One study found that 30.7% of elderly PD patients reported at least one OCS or a related disorder, compared to 21.1% in a healthy control group, with hoarding being notably more common among PD patients2. Another study highlighted that contamination obsessions and cleaning compulsions were present in both PD patients and controls, but no statistically significant difference was found between the groups1.
Neuropsychological Dysfunction in PD and OCD
Both PD and OCD are associated with dysfunction in the frontostriatal circuitry, which is crucial for motor and cognitive processes. A pilot study revealed that patients with either condition exhibited impairments in visuoconstructional tasks, suggesting common selective deficits due to basal ganglia involvement3. This shared neuropsychological profile underscores the potential overlap in the pathophysiology of PD and OCD.
Personality Disorders in PD Patients
The prevalence of personality disorders, particularly OCPD, is notably high in PD patients. A study found that 40% of PD patients were diagnosed with OCPD, compared to only 10% of healthy controls10. This high frequency of OCPD in PD patients does not appear to be related to the duration of the disease or dopaminergic therapy, indicating a potential intrinsic link between PD and OCPD10.
Impact of Comorbid Personality Disorders on Treatment Outcomes
The presence of comorbid personality disorders, including OCPD, can significantly affect treatment outcomes in OCD patients. Studies have shown that certain personality disorders, such as schizotypal and narcissistic PDs, are associated with poorer treatment outcomes in OCD patients6. This suggests that the management of PD patients with comorbid OCPD may require tailored therapeutic approaches to address both motor and psychiatric symptoms effectively.
Deep Brain Stimulation as a Treatment for PD and OCD
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) has shown promise in treating both PD and severe OCD symptoms. A case report documented a PD patient with severe OCD who experienced dramatic improvements in both motor and OCD symptoms following bilateral STN stimulation8. This finding opens new avenues for the surgical treatment of severe and medically intractable OCD in PD patients.
Conclusion
The intersection of OCPD and PD presents a complex clinical picture that necessitates a comprehensive approach to diagnosis and treatment. The high prevalence of OCPD in PD patients, coupled with the shared neuropsychological deficits and the potential for improved outcomes with interventions like DBS, highlights the need for further research and specialized care strategies. Understanding and addressing the psychiatric dimensions of PD can significantly enhance the quality of life for affected individuals.
Sources and full results
Most relevant research papers on this topic
Obsessive Compulsive Symptoms, Obsessive Compulsive Disorder and Related Disorders in Idiopathic Parkinson’s Disease
Idiopathic Parkinson's Disease patients have a higher prevalence of obsessive-compulsive symptoms and related disorders compared to healthy controls.
Prevalence of Obsessive-Compulsive Symptoms in Elderly Parkinson Disease Patients: A Case-Control Study.
Obsessive-compulsive symptoms are prevalent in elderly Parkinson's disease patients, with hoarding being more common than in the general population.
Observational StudyA pilot study of the neuropsychology of obsessive-compulsive disorder and Parkinson's disease: basal ganglia disorders.
OCD and Parkinson's disease patients show common selective deficits in visuoconstructional tasks, but not immediate memory and focused attention, suggesting basal ganglia involvement in both disorders.
Observational Study
Highly CitedCorrelates of DSM-III personality disorder in obsessive-compulsive disorder.
OCD patients exhibit a wide range of personality traits, but anxiety, phobic, and obsessive-compulsive symptoms do not uniquely predict personality disorders.
Observational StudyParkinsons Disease and Obsessive-Compulsive Phenomena: A Systematic Review
The relationship between Parkinson's disease and obsessive-compulsive disorder (OCD) is unclear, with methodological problems in the literature and potential correlations between motor symptoms and specific OCD or personality traits.
Systematic ReviewThe effect of personality disorders on treatment outcomes in patients with obsessive-compulsive disorders.
Comorbid personality disorders, particularly cluster A disorders, are associated with poorer treatment outcomes in patients with obsessive-compulsive disorder.
Systematic ReviewObsessive-Compulsive (Anankastic) Personality Disorder in the ICD-11: A Scoping Review
The ICD-11 dimensional model of obsessive-compulsive personality disorder (OCPD) is diagnostically valid and clinically useful, with the anankastia domain overlapping with DSM-5 traits and supporting its diagnostic validity.
Systematic ReviewEffect of subthalamic nucleus stimulation on obsessive-compulsive disorder in a patient with Parkinson disease. Case report.
Subthalamic nucleus stimulation effectively improves both Parkinson's disease and OCD symptoms in a patient, offering new possibilities for surgical treatment of severe OCD.
Case ReportHighly CitedObsessive–compulsive disorder and personality disorder
Personality pathology is highly prevalent among individuals with OCD living in the community, and routine assessment is crucial for assessing help-seeking behavior and treatment response.
Obsessive Compulsive Personality Disorder and Parkinson’s Disease
Parkinson's disease patients have a high frequency of obsessive-compulsive personality disorder, which is not related to disease duration or dopaminergic therapy.
Observational Study
Rigorous Journal