Over-the-counter treatments for anxiety
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Common Over-the-Counter (OTC) Treatments for Anxiety
Several over-the-counter products are used by people to manage anxiety symptoms, especially while waiting for or alongside prescription treatments. The most commonly studied OTC products for anxiety include herbal medicines and dietary supplements such as kava, lavender, saffron, probiotics, Galphimia glauca, and valerian. These products have been the focus of most research, while other popular remedies like chamomile and St John's Wort have less evidence supporting their use for anxiety, despite being commonly used by the public 15.
Herbal Medicines and Dietary Supplements for Anxiety Relief
Herbal medicines such as kava, lavender, and valerian are among the most frequently evaluated OTC products for anxiety. These products are available in various forms and dosages, and some studies suggest they may help reduce anxiety symptoms. However, the evidence base is mixed, and more research is needed to compare these products directly with conventional treatments and to evaluate less-studied remedies like chamomile and St John's Wort 15.
OTC Sedative Drugs and Antihistamines
Some first-generation antihistamines, such as diphenhydramine and chlorpheniramine, are available over the counter and have properties similar to prescription selective serotonin reuptake inhibitors (SSRIs). These antihistamines have been used for decades and are reported to have some effectiveness in treating anxiety and panic symptoms. They are generally considered safe for self-management, including during pregnancy, but can cause sedative and anticholinergic side effects . Expert assessments also highlight the importance of combining OTC sedative drugs with non-drug strategies, such as stress management techniques, for optimal self-help in stressful situations .
Effectiveness and Safety of OTC Treatments
While some OTC products, especially certain herbal medicines and antihistamines, show promise for managing anxiety, the overall evidence is limited. Some research suggests that no OTC medications are consistently effective for relieving anxiety, stress, or depression, but that certain plants and essential oils may help reduce symptoms . The safety and effectiveness of these products can vary, and more research is needed to provide clear guidance for consumers 145.
Conclusion
OTC treatments for anxiety include a range of herbal medicines, dietary supplements, and sedative antihistamines. While some products like kava, lavender, valerian, diphenhydramine, and chlorpheniramine have been studied and may offer some benefit, the evidence is not strong or consistent for most OTC options. Non-drug approaches and responsible self-management are also important. More research is needed to evaluate commonly used but less-studied products and to compare OTC treatments with conventional therapies for anxiety.
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