Peptide supplement dosage recommendations
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Collagen Peptide Supplement Dosage Recommendations
Research on collagen peptide supplementation for joint and skin health suggests a range of effective dosages. For knee osteoarthritis, daily supplementation with 2.5 g, 5.0 g, or 10.0 g of high-functional Type J bovine collagen peptides over 90 days showed significant improvements in pain, joint function, and quality of life. Notably, even the lowest dose of 2.5 g was as effective as 10.0 g of conventional collagen peptides, indicating that lower doses can be sufficient for therapeutic benefits . For skin health, a daily intake of 1.65 g (1650 mg) of collagen peptide for 12 weeks improved skin hydration, elasticity, and reduced wrinkling, with no reported side effects .
Soybean Bioactive Peptide Supplement Dosage
Studies in mice have evaluated the effects of soybean bioactive peptides (SBP) on energy metabolism and exercise performance. Doses tested included 110 mg/kg, 220 mg/kg, and 440 mg/kg body weight per day. The highest dose (440 mg/kg) produced the greatest improvements in muscle energy metabolism, while both medium (220 mg/kg) and high doses enhanced exercise performance and endurance. The medium dose was identified as optimal for improving exercise endurance and anti-fatigue effects 23.
Small Peptide Supplement Dosage in Animal Nutrition
In animal studies, small peptide supplementation has been shown to improve growth, immunity, and gut health. For laying hens, the optimal dosage was 4.5 g/kg of feed, which maximized growth rate, immune function, and gut integrity . In geese, yeast peptide supplementation at 200–300 mg/kg of feed improved growth performance and nutrient digestibility, with 200 mg/kg or 300 mg/kg being the most effective . For weaned piglets, antimicrobial peptide supplementation at 500 mg/kg of feed enhanced humoral immune responses in a dose-dependent manner .
Peptide Dosage for Anti-Aging Effects
A meta-analysis in Caenorhabditis elegans found that peptide supplementation at doses ranging from 0.1–1 kg/m³ provided the best anti-aging effects, including increased lifespan and improved health markers .
Conclusion
Peptide supplement dosage recommendations vary by peptide type and intended benefit. For collagen peptides in humans, daily doses as low as 1.65–2.5 g are effective for skin and joint health. For plant-derived and small peptides in animal studies, optimal dosages range from 110–440 mg/kg body weight or 200–500 mg/kg of feed, depending on the species and desired outcome. Always consider the specific peptide, target population, and health goal when determining the appropriate dosage.
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