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These studies suggest that early prostate cancer often shows no symptoms, but later signs can include urinary difficulties, blood in urine or semen, and pain with ejaculation.
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Prostate cancer often goes unnoticed in its early stages as it typically does not cause pain or noticeable symptoms. Many men are diagnosed through routine health screenings, such as a blood test for prostate-specific antigen (PSA) or a digital rectal exam (DRE) . PSA is a protease produced by the prostate, and elevated levels can indicate prostate cancer, although they can also be elevated in benign conditions like benign prostatic hyperplasia (BPH) and prostatitis. DRE can help detect abnormalities in the prostate that might suggest cancer.
As prostate cancer progresses, it can cause a variety of symptoms primarily related to urinary and sexual function. Men may experience difficulty starting or stopping the flow of urine, a feeling of incomplete bladder emptying, and blood in the urine or semen. Additionally, pain during ejaculation and erectile dysfunction can also be signs of prostate cancer . These symptoms overlap significantly with other non-cancerous conditions affecting the prostate, making it challenging to diagnose based solely on symptoms.
In more advanced stages, prostate cancer can present with symptoms related to metastasis. Unexplained bone pain, particularly in the back, can be an early sign of metastatic prostate cancer . Other severe symptoms include acute urinary retention, bilateral hydronephrosis, and spinal cord compression, although these are less common. In rare cases, patients may present with supraclavicular lymphadenopathy or liver abnormalities, which can be identified through biopsy and PSA staining.
Prostate cancer is most frequently diagnosed in elderly men, with a significant increase in incidence among men over 50 years old . Family history and genetic factors also play a crucial role in the risk of developing prostate cancer. The disease is more prevalent in regions with a high human development index and has a higher incidence and mortality rate among African-American men.
Recognizing the signs and symptoms of prostate cancer is crucial for early detection and effective treatment. While early stages may be asymptomatic, routine screenings like PSA tests and DREs are vital for identifying potential cases. Symptoms such as urinary difficulties, blood in urine or semen, and erectile dysfunction should prompt further investigation, although they are not exclusive to prostate cancer. Advanced disease may present with bone pain and other severe symptoms, indicating metastasis. Understanding these signs and maintaining regular health check-ups can significantly improve outcomes for men at risk of prostate cancer.
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