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Some studies suggest artificial sweeteners may help reduce energy intake and body weight, while other studies indicate they may contribute to obesity and diabetes by altering the gut-brain axis, microbiome, and glucose homeostasis.
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Artificial sweeteners are widely used as sugar substitutes to help reduce calorie intake and manage conditions like obesity and diabetes. However, their effectiveness and safety remain subjects of ongoing debate. This synthesis aims to present the current understanding of the role of artificial sweeteners in obesity and diabetes based on recent research findings.
Impact on Weight and Energy Intake:
Microbiome and Metabolic Effects:
Appetite and Satiety:
Long-term Health Risks:
Diabetes Management:
The role of artificial sweeteners in managing obesity and diabetes is complex and multifaceted. While they can help reduce calorie intake and modestly aid in weight loss, their impact on the gut microbiome and glucose metabolism raises concerns. Additionally, the long-term health risks associated with high consumption of artificial sweeteners warrant further investigation. Overall, the current evidence suggests that while artificial sweeteners can be a useful tool in specific contexts, their benefits and risks must be carefully weighed, especially for individuals with diabetes and obesity.
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