7 papers analyzed
These studies suggest that while CRISPR and gene editing in humans have potential benefits, they also raise significant safety and ethical concerns, including off-target changes, genetic modifications passed to future generations, ecological impacts, and the need for stringent regulations and public engagement.
CRISPR/Cas9 gene editing technology has revolutionized the field of genetic engineering, offering unprecedented precision and potential for therapeutic applications. However, its use, particularly in humans, raises significant safety and ethical concerns. This synthesis explores the key insights from multiple research papers on the safety and ethical implications of CRISPR and gene editing in humans.
Safety Concerns:
Ethical Concerns:
Regulatory and Social Considerations:
The use of CRISPR/Cas9 in human gene editing presents both promising therapeutic potential and significant safety and ethical challenges. Key concerns include off-target effects, the creation of genetic mosaics, and the dual-use potential of the technology. Ethical issues revolve around germline editing, human enhancement, and the need for informed consent. To mitigate these risks, stringent regulations, international ethical standards, and active public engagement are essential.
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