Side effects of thc drops

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Side Effects of THC Drops

Introduction to THC Drops

Delta-9-tetrahydrocannabinol (THC) is the primary psychoactive component of cannabis, often used for its potential analgesic properties. THC drops, a liquid form of THC, are commonly administered orally. While they may offer pain relief, they also come with a range of side effects that can impact their therapeutic use.

Common Side Effects of THC Drops

Somnolence and Dizziness

One of the most frequently reported side effects of THC drops is somnolence, or excessive sleepiness. This sedative effect can be significant enough to interfere with daily activities 12. Dizziness is another common side effect, which can lead to a feeling of unsteadiness and increase the risk of falls 12.

Ataxia and Blurred Vision

At higher doses, THC can cause ataxia, a condition characterized by a lack of muscle coordination, which can affect speech, eye movements, and the ability to swallow . Blurred vision is also reported, which can impair the ability to perform tasks that require clear eyesight .

Psychotropic Effects

THC is known for its psychotropic effects, which include euphoria, anxiety, and confusion. These effects are usually mild but can be distressing for some users . The psychotropic nature of THC can also lead to altered mental states, making it difficult for users to focus or think clearly .

Nausea and Gastrointestinal Issues

Nausea is another side effect associated with THC drops. While THC is sometimes used to combat nausea, particularly in chemotherapy patients, it can paradoxically cause nausea in some individuals . Gastrointestinal discomfort, including stomach pain and changes in appetite, may also occur .

Conclusion

While THC drops have potential analgesic benefits, their side effects can be significant and varied. Common side effects include somnolence, dizziness, ataxia, blurred vision, psychotropic effects, and nausea. These side effects can limit the therapeutic use of THC drops, particularly at higher doses. Therefore, it is crucial for users and healthcare providers to weigh the benefits against the potential adverse effects when considering THC drops for pain management.

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Most relevant research papers on this topic

The analgesic properties of delta‐9‐tetrahydrocannabinol and codeine

THC, 10mg, shows mild analgesic potential for cancer pain, but at 20mg, it causes side effects and may not be therapeutically useful due to adverse reactions.

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364citations

·R. Noyes et al.

The analgesic effect of oral delta-9-tetrahydrocannabinol (THC), morphine, and a THC-morphine combination in healthy subjects under experimental pain conditions

THC and THC-morphine combination show a slight additive analgesic effect in electrical stimulation tests, but both drugs show no significant analgesic effect in pressure and heat tests.

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2003·

203citations

·M. Naef et al.

Pharmacokinetics and Pharmacodynamics of Cannabinoids

Cannabinoids, including THC and CBD, can enhance well-being and relaxation, with potential therapeutic benefits including analgesia, muscle relaxation, immunosuppression, sedation, mood improvement, and cancer cell death.

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2003·

1365citations

·F. Grotenhermen

Ingestion of a THC-Rich Cannabis Oil in People with Fibromyalgia: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

THC-rich cannabis oil can be a low-cost, well-tolerated therapy that reduces symptoms and improves quality of life for fibromyalgia patients without intolerable adverse effects.

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2020·

71citations

·C. Chaves et al.

The effect of five day dosing with THCV on THC-induced cognitive, psychological and physiological effects in healthy male human volunteers: A placebo-controlled, double-blind, crossover pilot trial

Repeated THCV administration for five days in healthy male volunteers showed a protective effect on delayed verbal recall and inhibited THC-induced increased heart rate, while potentiating memory intrusions.

RCTVery Rigorous JournalHighly Cited

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76citations

·Amir Englund et al.

A randomised controlled trial of vaporised Δ9-tetrahydrocannabinol and cannabidiol alone and in combination in frequent and infrequent cannabis users: acute intoxication effects

Low doses of CBD combined with THC can enhance intoxication, while high doses reduce it, with infrequent cannabis users particularly affected by this effect.

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145citations

·N. Solowij et al.

The treatment of spasticity with Δ9-tetrahydrocannabinol in persons with spinal cord injury

THC is an effective and safe drug for treating spasticity in spinal cord injury patients, with a therapeutic effect achieved at 15-20 mg per day.

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2007·

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·U. Hagenbach et al.

Delta 9-tetrahydrocannabinol (THC) is effective in the treatment of tics in Tourette syndrome: a 6-week randomized trial.

THC is effective and safe in reducing tics in Tourette syndrome patients, suggesting the central cannabinoid receptor system may play a role in the condition.

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237citations

·K. Müller-Vahl et al.

Acute effects of a single, oral dose of d9-tetrahydrocannabinol (THC) and cannabidiol (CBD) administration in healthy volunteers.

THC has marked acute behavioral and physiological effects, while CBD is safe and well-tolerated in healthy volunteers.

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·R. Martín-Santos et al.

The treatment of spasticity with Delta9-tetrahydrocannabinol in persons with spinal cord injury.

THC is an effective and safe drug for treating spasticity in spinal cord injury patients, with a therapeutic effect achieved at a dose of at least 15-20 mg per day.

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·U. Hagenbach et al.

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