10 papers analyzed
These studies suggest that statins are generally safe and effective in reducing cardiovascular disease risk, with rare but potential adverse effects on muscle and liver.
17 papers analyzed
Statins are widely prescribed medications used to lower cholesterol levels and reduce the risk of cardiovascular diseases. Despite their proven efficacy, concerns about their safety, particularly regarding muscle toxicity, liver function, and other potential adverse effects, persist. This synthesis aims to provide a comprehensive overview of the safety profile of statins based on multiple research studies.
Muscle Toxicity and Myopathy
Liver Function
Diabetes Risk
Cognitive Function
Cancer Risk
Haemorrhagic Stroke
Overall Safety and Tolerability
Statins are safe and effective for most patients, with a low incidence of serious adverse effects. While there are some risks, such as muscle toxicity, liver enzyme elevations, and a modest increase in diabetes risk, these are outweighed by the significant cardiovascular benefits. Statins do not increase the risk of cancer and are generally well-tolerated, making them a valuable tool in the prevention and management of cardiovascular diseases.
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