Stroke volume
Searched over 200M research papers for "stroke volume"
Summary
10 papers analyzed
These studies suggest that stroke volume is influenced by various factors including cardiac parameters, respiration, and clinical conditions, and is relevant in predicting fluid responsiveness and clinical outcomes in different medical contexts.
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Stroke Volume: Key Insights from Recent Research
Introduction to Stroke Volume
Stroke volume (SV) is a critical hemodynamic parameter that measures the volume of blood ejected by the heart with each beat. It is a vital indicator of cardiac function and is particularly significant in various medical conditions, including pulmonary hypertension and stroke. This article synthesizes recent research findings on stroke volume, its clinical significance, and its implications for patient outcomes.
Stroke Volume in Pulmonary Hypertension
Clinical Significance and Measurement
Stroke volume is a crucial parameter in managing pulmonary hypertension (PH) as it directly reflects right ventricular function without the compensatory effects of increased heart rate, unlike cardiac output. Research indicates that a change of 10 mL in stroke volume is considered clinically significant in PH patients, providing a benchmark for evaluating therapeutic interventions.
Prognostic Value
The ability to measure stroke volume noninvasively makes it an essential tool for monitoring treatment efficacy in PH. The relationship between stroke volume changes and improvements in exercise capacity, as measured by the 6-minute walk test, underscores its prognostic value.
Stroke Volume and Brain Volume Changes Post-Stroke
Early Brain Volume Changes
Studies have shown that brain volume decreases significantly within the first month after an acute ischemic stroke. This volume loss is associated with age and the presence of deep white matter hyperintensities, rather than the severity of the initial stroke lesion . The median brain volume decrease observed was 6 mL, equating to a 0.5% reduction, highlighting the importance of early intervention and monitoring in stroke patients .
Functional Outcomes
Larger brain volumes at the time of stroke have been linked to better functional outcomes. Patients with greater brain volumes tend to have lower modified Rankin Scale scores, indicating less disability and better recovery prospects. This suggests that brain volume could serve as a protective biomarker and a predictor of long-term outcomes in stroke patients.
Hospital Volume and Stroke Outcomes
Impact of Hospital Volume
Research has demonstrated that higher hospital volumes of stroke admissions are associated with lower mortality rates. Patients treated in high-volume facilities (more than 200 strokes per year) have significantly better outcomes compared to those in low-volume hospitals. This finding emphasizes the importance of specialized care and the potential benefits of centralizing stroke treatment in high-volume centers.
Stroke Volume and Heartbeat-Evoked Responses
Relationship with Cardiac Parameters
The relationship between stroke volume and heartbeat-evoked responses (HERs) has been explored, revealing that HERs co-fluctuate with stroke volume on a beat-to-beat basis. This relationship is evident when no correction for cardiac artifacts is performed, suggesting that stroke volume fluctuations can influence neural responses. This insight could have implications for understanding the neurocardiac interactions and their role in various physiological and pathological states.
Conclusion
Stroke volume is a vital parameter in both cardiac and neurological contexts. Its measurement and monitoring can provide significant insights into patient prognosis and treatment efficacy, particularly in conditions like pulmonary hypertension and stroke. The relationship between stroke volume and brain volume changes post-stroke, as well as its impact on functional outcomes, underscores its importance in clinical practice. Additionally, the association between hospital volume and stroke outcomes highlights the need for specialized care in high-volume centers to improve patient survival and recovery.
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