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These studies suggest that normal serum triglyceride levels range from 70-120 mg/dL, with variations based on age, sex, weight, and fasting status.
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Triglycerides are a type of fat found in the blood, and their levels are an important indicator of metabolic health. Understanding the normal range of triglyceride values is crucial for assessing cardiovascular risk and overall health.
In healthy adults, the normal range for fasting serum triglycerides is generally considered to be below 150 mg/dL. However, some studies suggest that levels below 100 mg/dL may be more optimal for reducing the risk of coronary heart disease (CHD). The National Cholesterol Education Program defines a fasting triglyceride level below 150 mg/dL as normal, but observational data indicate that levels above 100 mg/dL can still predict CHD events.
Triglyceride levels can vary based on age and sex. For instance, males aged 40-49 years tend to have higher triglyceride values compared to other age groups, while females do not show significant age-related variations. Additionally, overweight males generally have higher triglyceride levels than those of normal weight. In a study of 385 blood donors, the upper range for triglycerides was found to be 2.28-2.85 mmol/L (2.0-2.5 g/L), with values being age and sex-dependent.
Postmenopausal women tend to have higher triglyceride levels compared to premenopausal women. This increase is observed across various lipoprotein subclasses, including very low-density lipoprotein (VLDL) and low-density lipoprotein (LDL).
Non-fasting triglyceride levels also provide valuable insights. In healthy Dutch males and females, non-fasting triglyceride concentrations were higher in the evening, with 95% of males having levels below 4.6 mmol/L and females below 3.7 mmol/L. These non-fasting values can be used to detect groups at risk for atherosclerosis.
Elevated triglyceride levels are associated with an increased risk of coronary heart disease. A meta-analysis involving 29 studies and over 262,000 participants found a moderate but significant association between higher triglyceride values and CHD risk. This association remains significant even after adjusting for other established risk factors.
Understanding the normal range of triglyceride values is essential for assessing cardiovascular risk and overall metabolic health. While fasting levels below 150 mg/dL are generally considered normal, levels below 100 mg/dL may be more optimal for reducing CHD risk. Age, sex, and menopausal status significantly influence triglyceride levels, and non-fasting values also provide important health insights. Monitoring and managing triglyceride levels can play a crucial role in preventing cardiovascular diseases.
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