Verisol collagen

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Verisol Collagen: Benefits for Skin Health

Introduction to Verisol Collagen

Verisol collagen, a specific bioactive collagen peptide (BCP), has gained attention for its potential benefits in skin health, particularly in reducing wrinkles and enhancing dermal matrix synthesis. This article synthesizes findings from recent studies to provide a comprehensive overview of the effects of Verisol collagen on skin aging.

Reduction of Skin Wrinkles

Clinical Evidence on Wrinkle Reduction

A double-blind, placebo-controlled study investigated the impact of Verisol collagen on eye wrinkle formation in women aged 45-65 years. Participants were randomized to receive either 2.5 g of Verisol collagen or a placebo daily for 8 weeks. The study found a statistically significant reduction in eye wrinkle volume by 20% after 4 and 8 weeks of intake compared to the placebo group. This effect persisted even 4 weeks after the last administration of Verisol collagen, indicating a long-lasting benefit .

Enhancement of Dermal Matrix Synthesis

Procollagen I, Elastin, and Fibrillin Biosynthesis

The same study also assessed the biosynthesis of key skin components such as procollagen I, elastin, and fibrillin. After 8 weeks of Verisol collagen intake, there was a significant increase in the content of procollagen type I (65%) and elastin (18%) compared to the placebo group. Although fibrillin content increased by 6%, this change was not statistically significant . These findings suggest that Verisol collagen not only reduces wrinkles but also enhances the structural integrity of the skin.

Broader Skin Health Benefits

Hydration, Elasticity, Roughness, and Density

Another randomized, placebo-controlled, blind study evaluated the effects of a nutraceutical containing 2.5 g of collagen peptides, along with other ingredients, on various skin parameters. The study included 72 healthy women aged 35 years or older. Results showed significant improvements in skin hydration, elasticity, roughness, and density in the group that received the collagen supplement compared to the placebo group. These benefits were maintained even 4 weeks after discontinuing the supplement, highlighting the sustained positive effects of collagen intake .

Conclusion

Verisol collagen has demonstrated significant benefits in reducing skin wrinkles and enhancing dermal matrix synthesis, as well as improving overall skin health parameters such as hydration, elasticity, roughness, and density. These findings support the use of Verisol collagen as an effective supplement for combating skin aging and promoting healthier skin.

Sources and full results

Most relevant research papers on this topic

Oral Intake of Specific Bioactive Collagen Peptides Reduces Skin Wrinkles and Increases Dermal Matrix Synthesis

Oral intake of specific bioactive collagen peptides (Verisol®) significantly reduced skin wrinkles and increased dermal matrix synthesis in women aged 45-65 years.

RCTHighly Cited

2013·

136citations

·Ehrhardt Proksch et al.

A Collagen Supplement Improves Skin Hydration, Elasticity, Roughness, and Density: Results of a Randomized, Placebo-Controlled, Blind Study

Drinkable collagen supplement ELASTEN® significantly improves skin hydration, elasticity, roughness, and density, with sustained positive effects and well-tolerated results.

RCTVery Rigorous JournalHighly Cited

2019·

122citations

·L. Bolke et al.

Scientific opinion on the substantiation of a health claim related to VeriSol®P and a change in skin elasticity leading to an improvement in skin function pursuant to Article 13(5) of Regulation (EC) No 1924/2006.

The EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) found no evidence to support a cause-effect relationship between VeriSol®P consumption and improved skin function.

2013·

2citations

·Efsa Panel on Dietetic Products

Scientific Opinion on the substantiation of a health claim related to VeriSol®P and a change in skin elasticity leading to an improvement in skin function pursuant to Article 13(5) of Regulation (EC) No 1924/2006.

The consumption of VeriSol ® P does not establish a cause and effect relationship with a change in skin elasticity leading to an improvement in skin function.

2013·

3citations

Collagen and gelatin.

Collagen and gelatin are widely used in food, pharmaceutical, and cosmetic industries due to their biocompatibility, easy biodegradability, and weak antigenicity.

Highly Cited

2015·

434citations

·Dasong Liu et al.

Healing Process, Pain, and Health-Related Quality of Life in Patients with Venous Leg Ulcers Treated with Fish Collagen Gel: A 12-Week Randomized Single-Center Study

Fish collagen gel treatment improves healing, pain intensity, and quality of life in patients with venous leg ulcers, with greater improvements in physical symptoms and pain.

RCTRigorous Journal

2022·

8citations

·P. Mościcka et al.

A double-blind, placebo-controlled, randomised, clinical study on the effectiveness of collagen peptide on osteoarthritis.

Collagen peptides from pork skin and bovine bone show potential as nutritional supplements for managing osteoarthritis and maintaining joint health.

RCTRigorous JournalHighly Cited

2015·

99citations

·Suresh Kumar et al.

Collagen extract obtained from Nile tilapia (Oreochromis niloticus L.) skin accelerates wound healing in rat model via up regulating VEGF, bFGF, and α-SMA genes expression

Topical application of Nile tilapia collagen extract accelerates cutaneous wound healing in rats by stimulating macrophage recruitment, fibroblast proliferation, and angiogenesis.

RCTAnimal StudyRigorous Journal

2020·

65citations

·Z. Elbialy et al.

A Dermonutrient Containing Special Collagen Peptides Improves Skin Structure and Function: A Randomized, Placebo-Controlled, Triple-Blind Trial Using Confocal Laser Scanning Microscopy on the Cosmetic Effects and Tolerance of a Drinkable Collagen Supplement

A drinkable collagen supplement containing special collagen peptides significantly improves facial skin structure and function after 12 weeks of intake, while no improvements were found with a placebo.

RCT

2020·

16citations

·S. Laing et al.

An Update on the Clinical Efficacy and Safety of Collagen Injectables for Aesthetic and Regenerative Medicine Applications

Collagen-based injectables have shown clinical efficacy and safety in treating various soft tissue diseases, including integumental, gastrointestinal, musculoskeletal, and urogenital apparatus.

2023·

15citations

·L. Salvatore et al.

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