Vitamin b complex and hair growth

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The Role of Vitamin B Complex in Hair Growth

Introduction to Vitamin B Complex and Hair Growth

Vitamin B complex, a group of water-soluble vitamins, plays a crucial role in maintaining overall health, including the health of hair. This article explores the relationship between vitamin B complex and hair growth, drawing insights from recent research studies.

Vitamin B6 and Hair Growth Enhancement

Combined Effects with Azelaic Acid

A study investigated the effects of vitamin B6 in combination with azelaic acid on hair growth in animal models. The results demonstrated that the topical application of both substances significantly accelerated hair regrowth compared to other treatments. This combination not only promoted hair follicle elongation and thickness but also increased the number of basal cells in the treated areas. Additionally, the combined treatment elevated the expression of IGF-I, a growth factor, while reducing TGF-β1, which is associated with hair growth inhibition .

Vitamin B Complex Production from Hair Waste

Biochemical Valorisation of Hair Wastes

Another study explored an innovative approach to producing vitamin B complex using keratinase enzymes derived from Bacillus thuringiensis. This enzyme effectively broke down keratin in donkey hair, releasing essential amino acids. These amino acids were then utilized by Saccharomyces cerevisiae to biosynthesize vitamins B1, B2, and B12. This method not only provides an eco-friendly solution to managing hair waste but also highlights the potential of hair-based hydrolysate in vitamin B complex production .

Micronutrients and Hair Follicle Health

Role of Vitamins and Minerals in Hair Loss

A comprehensive review examined the role of various vitamins and minerals, including the B vitamins, in preventing and managing hair loss. Micronutrients are essential for the normal hair follicle cycle and cellular turnover, particularly in the rapidly dividing matrix cells of the follicle bulb. Deficiencies in these micronutrients can be a modifiable risk factor for alopecia. The review emphasized the need for large, double-blind, placebo-controlled trials to establish the effects of specific micronutrient supplementation on hair growth in individuals with micronutrient deficiencies and non-scarring alopecia .

Conclusion

The research indicates that vitamin B complex, particularly vitamin B6, plays a significant role in promoting hair growth and maintaining hair health. The combination of vitamin B6 with azelaic acid shows promising results in accelerating hair regrowth and enhancing hair follicle characteristics. Additionally, innovative methods of producing vitamin B complex from hair waste offer sustainable solutions. However, further research is necessary to fully understand the impact of vitamin B complex on hair growth and to establish effective supplementation strategies.

Sources and full results

Most relevant research papers on this topic

A Study for Verification of Hair Growth Effect of Azelaic Acid and Vitamin B 6

Azelaic acid and vitamin B6 combined have an additive effect on hair growth, promoting follicle elongation and thickness in mice.

2008·

0citations

·S. Yoon et al.

Biochemical characterisation and application of keratinase from Bacillus thuringiensis MT1 to enable valorisation of hair wastes through biosynthesis of vitamin B-complex.

Keratinase enzymes from Bacillus thuringiensis MT1 can effectively valorize hair waste by producing vitamin B-complex, offering an eco-friendly approach to managing hair waste.

2020·

37citations

·M. Hassan et al.

The Role of Vitamins and Minerals in Hair Loss: A Review

Micronutrients play a crucial role in normal hair follicle development and immune cell function, and deficiency may be a modifiable risk factor for alopecia.

Systematic ReviewHighly Cited

2018·

151citations

·Hind M. Almohanna et al.

Dietary supplement increases anagen hair rate in women with telogen effluvium: results of a double-blind, placebo-controlled trial

A specific L-cystine, medicinal yeast, pantothenic acid complex-based dietary supplement (Pantogar®) significantly improves and normalizes anagen hair rate in healthy women with telogen effluvium within 6 months of treatment.

RCT

2007·

56citations

·Nadine Lengg et al.

The Infatuation With Biotin Supplementation: Is There Truth Behind Its Rising Popularity? A Comparative Analysis of Clinical Efficacy versus Social Popularity.

Biotin supplementation's popularity is disproportionate to its insufficient clinical evidence supporting its efficacy in hair improvement, with no randomized controlled trials or clinical trials examining its effect on hair quantity or quality.

Literature Review

2017·

30citations

·Teo Soleymani et al.

Investigation of topical application of procyanidin B-2 from apple to identify its potential use as a hair growing agent.

Procyanidin B-2 therapy shows potential as a safe and promising cure for male pattern baldness, increasing the number of total hairs and terminal hairs after 6 months of use.

RCT

2000·

33citations

·A. Kamimura et al.

Dexpanthenol Promotes Cell Growth by Preventing Cell Senescence and Apoptosis in Cultured Human Hair Follicle Cells

D-panthenol stimulates hair growth by increasing cell viability, suppressing apoptosis markers, and elongating the anagen phase in human hair follicle cells.

In Vitro Study

2021·

10citations

·J. Shin et al.

The Effect of a Combination of an Arginine Silicate Complex and Magnesium Biotinate on Hair and Nail Growth in Rats (P06-026-19).

The combination of an arginine silicate complex and magnesium biotinate promotes hair and nail growth in rats, with the greatest effect observed in group 3.

RCTAnimal StudyVery Rigorous Journal

2019·

1citation

·J. Komorowski et al.

A Randomized Pilot Trial to Evaluate the Bioavailability of Natural versus Synthetic Vitamin B Complexes in Healthy Humans and Their Effects on Homocysteine, Oxidative Stress, and Antioxidant Levels

Natural and synthetic vitamin B complexes have comparable bioavailability and both show similar effects on antioxidants, homocysteine levels, and oxidative stress.

RCTRigorous Journal

2019·

22citations

·Meinrad Lindschinger et al.

Effects of Adrenalectomy on Pigmentation of Hair in Rats Fed a Deficient Diet

Adrenalectomy improves hair pigmentation in rats fed a deficient diet, indicating that the cortex of the adrenal gland plays a role in hair color.

Non-RCTAnimal Study

1945·

7citations

·E. O. Butcher

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