Vitamin b1 side effects blood pressure
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Vitamin B1 Side Effects on Blood Pressure
Introduction to Vitamin B1 and Blood Pressure
Vitamin B1, also known as thiamine, is an essential nutrient that plays a crucial role in energy metabolism and nerve function. Its effects on blood pressure have been studied in various contexts, including its impact on patients with schizophrenia, high normal blood pressure, and cardiac insufficiency.
Effects of Vitamin B1 in Schizophrenic Patients
A study involving schizophrenic male patients administered large doses of synthetic vitamin B1 both orally and intravenously for eight weeks found no significant changes in blood pressure. The study also noted no deleterious effects or clinical improvements related to the medication . This suggests that in the context of schizophrenia, vitamin B1 does not significantly impact blood pressure.
Impact on High Normal Blood Pressure
In a pilot study evaluating a nutraceutical containing Arginine, Lactobacillus Plantarum Lp-LDL, Coenzyme Q10, and Vitamin B1, significant reductions in both systolic (SBP) and diastolic blood pressure (DBP) were observed in patients with high normal blood pressure after three months of daily intake . This indicates that vitamin B1, as part of a combined supplement, may contribute to lowering blood pressure in individuals with high normal levels.
Thiamine in Cardiac Insufficiency
Research on patients with myocardial and pulmonary insufficiency treated post-operatively in the ICU revealed that incremental doses of vitamin B1 led to a rise in blood pressure by at least 20 mmHg and a moderate elevation of central venous pressure by 3 mmHg . This suggests that thiamine can act as a mild peripheral vasodilator, reducing pump outflow impedance and increasing systolic blood pressure in patients with cardiac insufficiency.
Conclusion
The effects of vitamin B1 on blood pressure vary depending on the context. While it does not significantly alter blood pressure in schizophrenic patients, it can contribute to lowering blood pressure in individuals with high normal levels when combined with other nutraceuticals. Additionally, in patients with cardiac insufficiency, thiamine can increase blood pressure and central venous pressure. These findings highlight the nuanced role of vitamin B1 in blood pressure regulation across different health conditions.
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