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These studies suggest that vitamin B12 deficiency is associated with hair loss and that supplementation may help in some cases.
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Chronic telogen effluvium (CTE) is a common form of diffuse hair loss characterized by the abrupt onset of hair shedding lasting more than six months. Research indicates that Vitamin B12 deficiency is significantly more prevalent in patients with CTE compared to healthy controls. In a study involving 70 participants, 60% of CTE patients exhibited Vitamin B12 deficiency, whereas only 26% of the control group had similar deficiencies, highlighting a strong correlation between low Vitamin B12 levels and CTE.
Pregnancy is another period where hair loss can be exacerbated by Vitamin B12 deficiency. A study examining 85 women, including 50 pregnant women with chronic diffuse hair loss, found that those in their last two trimesters with severe hair loss had significantly lower levels of Vitamin B12 compared to non-pregnant women. This suggests that maintaining adequate Vitamin B12 levels during pregnancy is crucial for preventing hair loss.
Vitamin B12 deficiency can also lead to changes in hair pigmentation. Cases have been reported where individuals with Vitamin B12 deficiency experienced reversible hyperpigmentation of the skin and premature graying of hair. Treatment with Vitamin B12 injections led to the normalization of hair and skin pigmentation, underscoring the importance of this vitamin in maintaining healthy hair color .
Hair loss is a common complication following metabolic and bariatric surgery (MBS). A systematic review and meta-analysis revealed that 57% of patients experienced hair loss post-surgery. Although the study found that low levels of zinc, folic acid, and ferritin were more strongly associated with hair loss than Vitamin B12, it still highlighted the importance of monitoring and managing micronutrient levels, including Vitamin B12, to mitigate hair loss in these patients .
Micronutrients, including vitamins and minerals, play a critical role in the normal hair follicle cycle and cellular turnover. Deficiencies in these nutrients can lead to various forms of hair loss. While the exact role of Vitamin B12 in non-scarring alopecia remains to be fully elucidated, it is clear that maintaining adequate levels of this vitamin is essential for overall hair health. Large, double-blind, placebo-controlled trials are needed to further explore the impact of Vitamin B12 supplementation on hair growth in individuals with deficiencies.
Vitamin B12 plays a significant role in hair health, particularly in preventing chronic telogen effluvium and hair loss during pregnancy. It also affects hair pigmentation, with deficiencies leading to reversible changes. While other micronutrients like zinc and ferritin are also crucial, ensuring adequate Vitamin B12 levels is essential for maintaining healthy hair. Further research is needed to fully understand the therapeutic potential of Vitamin B12 supplementation in hair loss prevention and treatment.
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