Vitamins and their effects on nausea

Pro Research Analysisby

Searched over 200M research papers

Analyzed relevant papers

Vitamin B6 (Pyridoxine) and Nausea Relief

Vitamin B6 is widely studied for its effects on nausea, especially in pregnancy and chemotherapy. Multiple studies show that vitamin B6 supplementation significantly reduces the severity and frequency of nausea and vomiting in pregnant women and children undergoing chemotherapy 23456789+1 MORE. Systematic reviews and meta-analyses confirm that pyridoxine alone, or in combination with other substances, improves nausea symptoms in pregnancy . Vitamin B6 is also considered safe and effective, with minor side effects reported 3468.

Vitamin D3, Selenium, and Electrolytes in Nausea

Research indicates that women experiencing nausea and vomiting during pregnancy often have lower levels of vitamin D3, vitamin B6, selenium, and key electrolytes (potassium and magnesium) compared to those without symptoms. The reduction in these nutrients is more pronounced in the first trimester . While the study highlights an association, it does not directly test supplementation as a treatment for nausea.

Multivitamins and Nausea Prevention

Taking multivitamins before and during early pregnancy may reduce the risk of severe nausea and vomiting. Women who use periconceptional multivitamins are less likely to experience severe symptoms . Thiamine (vitamin B1) is also important, as deficiency in women with prolonged vomiting can lead to serious complications, and replacement is recommended for those with vomiting lasting more than three weeks .

Ginger Versus Vitamin B6 for Nausea

Several randomized controlled trials compare ginger and vitamin B6 for treating nausea and vomiting, especially in pregnancy. Both ginger and vitamin B6 significantly reduce nausea scores and vomiting episodes, with some studies suggesting ginger may be slightly more effective for nausea severity, though differences are often not statistically significant 346910. Both treatments are considered safe, with only minor side effects reported 346910.

Non-Pharmacological Alternatives: Bananas and Ginger Drinks

Non-pharmacological options like Ambon bananas (rich in vitamin B6 and flavonoids) and warm ginger drinks are also effective in reducing nausea and vomiting in pregnant women. Studies show both bananas and vitamin B6 are effective, with no significant difference in their ability to reduce symptoms . Similarly, both ginger drinks and vitamin B6 significantly decrease the frequency of nausea and vomiting in the first trimester .

Conclusion

Vitamin B6 is a well-supported, safe, and effective option for reducing nausea and vomiting, particularly in pregnancy and chemotherapy. Ginger is equally effective and may be slightly better for some individuals. Multivitamins, including vitamin D3 and thiamine, may help prevent or address deficiencies linked to nausea. Non-pharmacological options like bananas and ginger drinks also offer effective alternatives. Overall, vitamins—especially B6—play a significant role in managing nausea, with strong evidence supporting their use 12345678+2 MORE.

Sources and full results

Most relevant research papers on this topic

The Effect of Vitamin D3, Vitamin B6, Selenium and Some Electrolytes on the Women with Nausea and Vomiting of Pregnancy in Thi-Qar Government -Iraq

Nausea and vomiting during pregnancy are associated with a significant reduction in vitamin D3, vitamin B6, se, and Mg+2, with varying levels in the first and second trimesters.

Observational Study

2020·

0citations

·Nadia A. Jomah et al.

The effect of Vitamin B6 on chemotherapy induced nausea and vomiting in pediatric cancer

Vitamin B6 significantly reduces chemotherapy-induced nausea and vomiting in children with malignancy, especially in acute lymphocytic leukemia.

RCTVery Rigorous Journal

2020·

1citation

·M. Mousavi et al.

A randomized comparison of ginger and vitamin B6 in the treatment of nausea and vomiting of pregnancy.

Ginger and vitamin B6 both significantly reduce nausea and vomiting during pregnancy, with no significant difference in efficacy between the two treatments.

RCTHighly Cited

2003·

109citations

·M. Sripramote et al.

Comparison of the effectiveness of ginger and vitamin B6 for treatment of nausea and vomiting in early pregnancy: a randomized double-blind controlled trial.

Ginger is more effective than vitamin B6 for treating nausea and vomiting in pregnancy, with minor side effects.

RCTHighly Cited

2007·

91citations

·Porndee Chittumma et al.

The effects of pyridoxine (vitamin B6) supplementation in nausea and vomiting during pregnancy: a systematic review and meta-analysis

Pyridoxine supplementation alone and combined with an active ingredient significantly improves nausea and vomiting symptoms in pregnant women.

Meta-Analysis

2023·

10citations

·R. Jayawardena et al.

Comparing ginger and vitamin B6 for the treatment of nausea and vomiting in pregnancy: a randomised controlled trial.

Ginger is more effective than vitamin B6 for relieving nausea severity and is equally effective for decreasing the number of vomiting episodes in early pregnancy.

RCTHighly Cited

2009·

152citations

·Jenabi Ensiyeh et al.

EFEKTIVITAS PEMBERIAN PISANG AMBON (MUSA PARADISIACAL) DENGAN VITAMIN B6 DALAM MENURUNKAN INTENSITAS MUAL MUNTAH PADA IBU HAMIL TM 1 DI KLINIK LINA HINAI KIRI KEC.SECANGGANG

Giving Ambon bananas and vitamin B6 effectively reduces the intensity of nausea and vomiting in first trimester pregnant women at the Lina Hinai Kiri Secanggang Clinic.

2022·

1citation

·Khairani et al.

Overview of nausea and vomiting of pregnancy with an emphasis on vitamins and ginger.

Vitamin B6 and ginger are safe and effective treatments for nausea and vomiting of pregnancy, while periconceptional multivitamins and doxylamine are also effective.

2002·

68citations

·J. Niebyl et al.

A comparison between the effects of ginger, pyridoxine (vitamin B6) and placebo for the treatment of the first trimester nausea and vomiting of pregnancy (NVP)

Ginger is more effective than placebo for treating mild to moderate nausea and vomiting in pregnancy, and is comparable with vitamin B6.

RCT

2018·

62citations

·F. Sharifzadeh et al.

PENGARUH PEMBERIAN MINUMAN JAHE HANGAT TERHADAP PENURUNAN FREKUENSI MUAL MUNTAH PADA IBU TRIMESTER 1 DI PUSKESMAS SUNGAI DURIAN

Warm ginger drinks and vitamin B6 significantly reduce the frequency of nausea and vomiting in first trimester pregnant women.

2023·

1citation

·Ega Syavira et al.

Try another search

candida overgrowth symptoms

elements formed in stars

contraceptive pill side effects

probiotic efficacy factors

quasars in active galactic nuclei

particle arrangement in liquids