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These studies suggest that Vitex is generally safe with mild adverse events, but should be avoided during pregnancy and lactation, and may interfere with certain medications.
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Vitex agnus-castus (VAC), commonly known as chaste tree or chasteberry, is a herbal remedy traditionally used for various female reproductive conditions. This synthesis evaluates the safety of Vitex based on data from multiple research papers.
General Safety and Adverse Events:
Efficacy and Safety in Specific Conditions:
Comparative Safety:
Toxicity Studies:
Protective Effects:
Vitex agnus-castus is generally safe for use, with mild and reversible adverse events. It is effective for treating PMS, PMDD, and cyclic mastalgia, and is considered a safe alternative to conventional pharmaceutical treatments. However, caution is advised during pregnancy and lactation. Further high-quality studies are recommended to strengthen the evidence base for its safety and efficacy.
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