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Some studies suggest vomiting is an early predictor of death and a prominent symptom in ischemic brainstem strokes, while other studies indicate it can lead to misdiagnosis and delayed treatment due to nonspecific symptoms.
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Vomiting is a common but often overlooked symptom in stroke patients. Its presence can significantly impact the diagnosis, treatment, and prognosis of stroke. Understanding the relationship between vomiting and stroke can aid in early recognition and improve patient outcomes.
Vomiting occurs in varying frequencies across different types of strokes. A study examining stroke patients in the Kyoto prefecture found that vomiting was present in 14.5% of all stroke cases. When broken down by stroke type, vomiting was observed in 8.7% of cerebral infarction (CI) cases, 23.7% of cerebral hemorrhage (CH) cases, and 36.8% of subarachnoid hemorrhage (SAH) cases. This indicates that vomiting is more prevalent in hemorrhagic strokes compared to ischemic strokes.
Vomiting at the onset of a stroke is associated with a higher risk of mortality. The hazard ratio (HR) for death was significantly higher in patients who experienced vomiting, with HR values of 5.06 for all stroke patients, 5.27 for CI, 2.82 for CH, and 5.07 for SAH. This suggests that vomiting can be an early predictor of poor outcomes in stroke patients.
Vomiting can complicate the diagnosis of stroke, particularly in cases of ischemic brainstem strokes where vomiting may be the predominant symptom while other neurological signs are minimal or absent. This can lead to misdiagnosis as a gastrointestinal disorder, delaying appropriate treatment.
Women may experience unique stroke symptoms, including nausea and vomiting, more frequently than men. These symptoms are often under-recognized, leading to delays in diagnosis and treatment. Improving awareness and recognition of these symptoms can help reduce misdiagnosis and improve outcomes for female stroke patients.
The presence of vomiting and other nonspecific symptoms can lead to delays in treatment. Patients with posterior circulation strokes, who often present with symptoms like nausea and vomiting, experience longer times from emergency department evaluation to neurology evaluation and subsequent treatment . This delay can negatively impact the effectiveness of acute stroke therapies.
In rare cases, patients may develop cyclic vomiting syndrome (CVS) after a stroke. CVS is characterized by recurrent episodes of vomiting separated by symptom-free periods. A case study reported a 69-year-old woman who developed CVS following a left cerebral infarct, highlighting the need for awareness of this potential post-stroke complication.
Vomiting is a significant symptom in stroke patients that can influence diagnosis, treatment, and outcomes. Recognizing vomiting as a potential indicator of stroke, particularly in hemorrhagic cases and in women, can aid in timely and accurate diagnosis. Addressing the diagnostic challenges and treatment delays associated with vomiting can improve patient care and reduce mortality rates in stroke patients.
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