What is angina
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Summary
10 papers analyzed
These studies suggest angina is a common chest discomfort caused by myocardial oxygen deficiency, often due to coronary artery stenosis, and can be managed with medications and lifestyle changes to improve quality of life and prevent heart attacks.
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Understanding Angina: Causes, Symptoms, and Management
What is Angina?
Angina is a type of chest pain or discomfort caused by reduced blood flow to the heart muscle, indicating that the heart is not receiving enough oxygen. This condition is a common manifestation of ischemic heart disease (IHD) and is often a precursor to more severe cardiac events such as heart attacks .
Types of Angina
Typical Angina
Typical angina is characterized by substernal chest pain that is triggered by physical exertion or emotional stress and is relieved by rest or nitroglycerin. This type of angina is often associated with significant coronary artery disease (CAD) and is more common in men and younger women .
Variant Angina
Variant angina, also known as Prinzmetal's angina, is a rare form of angina that occurs spontaneously, often at rest, and is not necessarily related to physical exertion. It is marked by transient coronary artery spasms, which can lead to significant discomfort and potential complications.
Unstable Angina
Unstable angina is a more severe form of angina that can occur unpredictably and may not be relieved by rest or medication. It is often a warning sign of an impending heart attack and requires immediate medical attention.
Causes and Risk Factors
The primary cause of angina is myocardial ischemia, which occurs when the oxygen demand of the heart muscle exceeds the oxygen supply. This imbalance is often due to significant stenosis (narrowing) of the coronary arteries, typically caused by atherosclerosis. Other contributing factors include coronary vasoconstriction, microvascular dysfunction, and epicardial spasms.
Symptoms of Angina
Angina typically presents as chest pain or pressure, but the discomfort can also radiate to the arms, jaw, or upper back. The pain is a signal that the heart is not getting enough oxygen and can be triggered by various factors such as physical activity, emotional stress, large meals, smoking, and extreme temperatures .
Angina in Women
Women often experience angina differently than men. They may have less obstructive coronary artery disease but still suffer from significant morbidity and mortality due to microvascular disease. Women are also more likely to have atypical symptoms and may delay seeking care, which can lead to worse outcomes .
Diagnosis and Management
Diagnosis
The diagnosis of angina involves a thorough clinical evaluation, including a detailed history and physical examination. Diagnostic tests such as electrocardiograms (ECGs), stress tests, and coronary angiography are commonly used to assess the extent of coronary artery disease and myocardial ischemia .
Management
Management of angina focuses on relieving symptoms, improving quality of life, and preventing major cardiac events. Treatment options include:
- Pharmacologic Therapy: Medications such as beta-blockers, nitrates, calcium channel blockers, and ranolazine are commonly used to manage angina. In some cases, additional agents like trimetazidine, ivabradine, and nicorandil may be used .
- Revascularization: Procedures such as angioplasty and coronary artery bypass grafting (CABG) are indicated for high-risk individuals and those with poorly controlled symptoms despite optimal medical therapy.
- Advanced Therapies: For patients with refractory angina, options like enhanced external counterpulsation, transmyocardial revascularization, and stem cell therapy may be considered.
Conclusion
Angina is a significant clinical condition that indicates underlying ischemic heart disease. Understanding its types, causes, symptoms, and management strategies is crucial for improving patient outcomes and quality of life. Early diagnosis and appropriate treatment can help prevent severe cardiac events and enhance the ability of patients to lead active lives.
Sources and full results
Most relevant research papers on this topic
3
[WHAT IS AN ANGINA?].
3
3 Citations
1965
10
Unstable Angina A Classification
10
1,386 Citations
1989