What supplements lower blood sugar
Pro Research Analysisby 
Searched over 200M research papers
Supplements That Lower Blood Sugar
Managing blood sugar levels is crucial for individuals with diabetes or prediabetes. Various supplements have been studied for their potential to lower blood glucose levels. This article synthesizes the findings from multiple research studies on the effectiveness of different supplements in controlling blood sugar.
Chromium Supplements
Chromium Dinicocysteinate
Chromium dinicocysteinate (CDNC) has shown significant potential in lowering blood glucose levels. In a study involving Zucker diabetic fatty (ZDF) rats, CDNC supplementation resulted in lower fasting blood glucose, glycated hemoglobin (HbA1c), and markers of inflammation such as CRP and MCP-1. The study also noted increased levels of vitamin C and adiponectin, which are beneficial for glucose metabolism.
Chromium Picolinate and Chromium Dinicotinate
Other forms of chromium, such as chromium picolinate and chromium dinicotinate, were less effective compared to CDNC. These forms did not significantly impact blood glucose or inflammatory markers.
L-Cysteine
L-cysteine supplementation has been found to lower blood glucose and glycated hemoglobin levels. In ZDF rats, L-cysteine reduced fasting blood glucose by 18% and glycated hemoglobin by 8%. It also decreased markers of inflammation and oxidative stress, suggesting its potential in managing diabetes.
Curcumin and Curcuminoids
Curcumin, a compound found in turmeric, has been shown to lower fasting blood glucose levels. A meta-analysis of randomized controlled trials found that curcumin and curcuminoids significantly decreased fasting blood glucose and HbA1c levels in individuals with dysglycemia. However, the effects were not significant in non-diabetic individuals.
Exogenous Ketones
Exogenous ketone supplements, such as ketone monoesters and salts, have been shown to acutely lower blood glucose levels. A systematic review and meta-analysis found that these supplements significantly decreased mean blood glucose levels following ingestion.
Cinnamon
Cinnamon has insulin-mimicking properties that can help lower blood sugar levels. A clinical trial involving type 2 diabetes patients found that cinnamon supplementation significantly improved fasting plasma glucose levels and reduced body weight and BMI.
Propolis
Propolis, a resinous substance produced by bees, has shown promise in improving glycemic control. A randomized controlled trial found that propolis supplementation significantly decreased fasting blood sugar, postprandial glucose, and HbA1c levels. It also improved antioxidant status, making it a beneficial supplement for diabetes management.
Cheonggukjang and Red Ginseng Cheonggukjang
Cheonggukjang (fermented soybean paste) and red ginseng cheonggukjang have been studied for their effects on blood glucose levels. Supplementation with these products significantly lowered fasting blood glucose levels in individuals with impaired fasting glucose.
Probiotics
Probiotic supplements have been found to improve blood glucose levels and insulin sensitivity. A meta-analysis of randomized controlled trials showed that probiotics reduced fasting plasma glucose, serum insulin, and insulin resistance, particularly in pregnant women with gestational diabetes mellitus (GDM) and healthy pregnant women.
Conclusion
Several supplements, including chromium dinicocysteinate, L-cysteine, curcumin, exogenous ketones, cinnamon, propolis, cheonggukjang, and probiotics, have shown potential in lowering blood glucose levels. These supplements can be considered as complementary therapies for managing diabetes and prediabetes. However, further clinical trials are needed to confirm their efficacy and safety in diverse populations.
Sources and full results
Most relevant research papers on this topic