What are the symptoms of Marburg virus disease?

Introduction

Marburg virus disease (MVD) is a severe and often fatal illness caused by the Marburg virus, a member of the Filoviridae family. It is characterized by hemorrhagic fever and has similarities to Ebola, another member of the same virus family.

Key Insights from Research Papers

Symptoms of Marburg virus disease include fever, headache, muscle aches, vomiting, diarrhea, and bleeding from various parts of the body.
The replication of Marburg virus in human endothelial cells may contribute to the hemorrhagic symptoms and shock syndrome observed in infected individuals.
The incubation period for Marburg virus can range from 2 to 21 days, with severe hemorrhagic manifestations typically developing between 5 and 7 days after symptom onset.
Clinical features of MVD also include a characteristic rash, severe bleeding tendency, and central nervous system involvement.
There are no vaccines or antiviral treatments approved for MVD; however, supportive care such as rehydration and treatment of specific symptoms can improve survival.

Conclusion

Marburg virus disease presents with a range of symptoms that can include fever, headache, muscle pain, gastrointestinal issues, and severe hemorrhagic manifestations. The disease has a variable incubation period and can lead to shock and multi-organ involvement. While there is no specific treatment for MVD, supportive care is crucial for patient survival.

What are the symptoms of Marburg virus disease?

Summary

Introduction

Key Insights from Research Papers

Conclusion

Sources and full results

Marburg virus disease: a brief updated overview

Marburg virus disease presents with fever, headache, muscle aches, vomiting, diarrhoea, and bleeding, and supportive care can help manage symptoms and improve outcomes.

Replication of Marburg virus in human endothelial cells. A possible mechanism for the development of viral hemorrhagic disease.

Marburg virus replication in human endothelial cells may contribute to the development of viral hemorrhagic diseases and shock syndromes.

Marburg Virus Disease

Marburg virus disease (MVD) is a severe hemorrhagic fever caused by the Marburg virus, a genetically unique zoonotic RNA virus of the filovirus family.

Marburg virus disease

Marburg virus disease, transmitted from African green monkeys, causes headaches, fever, diarrhoea, rash, severe bleeding, and central nervous system involvement.

Marburg Virus Infection Detected in a Common African Bat

Marburg virus infection has been detected in a common African fruit bat, expanding the known range of the virus and indicating more areas at risk for hemorrhagic fever outbreaks than previously realized.

Transcriptional Profiling of the Immune Response to Marburg Virus Infection

The immune response to Marburg virus infection in primates shows three stages, with the earliest response being an interferon-like response, and a Th2-skewed response during late stages, potentially contributing to disease pathogenesis.

Marburg Virus Disease – A Mini-Review

Marburg virus disease (MVD) is a highly fatal disease caused by the Marburg virus (MARV), with molecular detection techniques and vaccines being effective in diagnosis and prevention.

MARBURG-VIRUS DISEASE IN KENYA

Marburg-virus disease was first identified in Kenya in 1980, but no further cases were reported.

Pathogenicity and virulence of Marburg virus

This review aims to improve understanding of Marburg virus diseases and enhance clinical management, addressing limitations in future medical research and enhancing clinical management.

Multidistrict Outbreak of Marburg Virus Disease-Uganda, 2012.

The 2012 Marburg virus outbreak in Uganda resulted in 15 fatal cases, but with contact tracing, active surveillance, and community mobilization, the outbreak was successfully contained 14 days after initial detection.

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