10 papers analyzed
These studies suggest that the symptoms of peptic ulcer disease include abdominal pain, nausea, vomiting, and weight loss.
Peptic ulcer disease (PUD) is a condition characterized by sores or erosions in the lining of the stomach, duodenum, or esophagus. It is primarily caused by an imbalance between aggressive factors like gastric acid and pepsin, and protective factors such as the mucosal lining. Common causes include Helicobacter pylori infection and the use of nonsteroidal anti-inflammatory drugs (NSAIDs).
Epigastric Pain:
Nocturnal Pain:
Variable Symptoms:
Complications:
Symptom Variability:
Peptic ulcer disease manifests primarily through epigastric pain, which varies in timing depending on whether the ulcer is gastric or duodenal. Nocturnal pain is also a significant symptom, especially in duodenal ulcers. Other symptoms include nausea, vomiting, weight loss, and in severe cases, bleeding and perforation. The presentation of symptoms can vary widely, particularly in older adults and those on certain medications.
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