A. Hunter
Jun 1, 1953
Citations
0
Influential Citations
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Citations
Journal
British journal of pharmacology and chemotherapy
Abstract
The compound 5:6-dithiadecamethylene 1:10bis(trimethylammonium iodide) was synthesized by Andrews, Bergel, and Morrison (1953), and given the serial number Ro 3-0386. On preliminary investigation it proved to be a myoneural blocking agent with an action rather like that of decamethonium (Randall, personal communication). Since this latter drug has been found in clinical anaesthesia to have certain disadvantages (Gray, 1950; Hunter, 1950), it seemed worth while to study the new compound in some detail in the hope that it might be more satisfactory.