A. Jamaludin, M. Mohamad, V. Navaratnam
Feb 1, 1988
Citations
0
Influential Citations
21
Citations
Quality indicators
Journal
British journal of clinical pharmacology
Abstract
The hydrochloride, sulphate and ethylcarbonate salts of quinine were given in single oral doses (600 mg base equivalent) to nine healthy male subjects according to a cross-over design. No statistically significant differences were noted in the plasma drug concentration-time profiles although inter- and intra-subject variation in AUC, Cmax and tmax values was appreciable. The ethylcarbonate salt may be preferred for use in paediatric patients because of its neutral taste.