R. Manske
Mar 1, 1931
Citations
0
Influential Citations
5
Citations
Journal
Canadian journal of research
Abstract
Degradation of calycanthine, by a method which has heretofore not been applied to alkaloids, namely, benzoylation with subsequent treatment with alkali, has yielded a well-defined crystalline substance, shown by analysis and synthesis to be benzoyl-N-methyltryptamine. The alternative, benzoyl-1-methyltryptamine, has also been synthesized for purpose of comparison. The bearing of the degradation product on the constitution of calycanthine is discussed. The partial structure developed for the alkaloid differs considerably from any that has been previously suggested for a natural product.