Shi‐Ting Wen
2008
Citations
0
Influential Citations
1
Citations
Journal
Journal of Sichuan University
Abstract
In acidic condition,the nitrogen in pefloxacin mesylate was easily protonated and formed ion-complexes with negative ion AuCl-4,the ion-complexes were extacted and carried by dichloromethane,when the ion-complexes entered a reversed micellar of cetyltrimethylammonium chlorine containing luminol,the dissociated AuCl-4 reacted with luminol and produced an analytical chemiluminescnece signal.In the optimum conditions,the linear range is 0.001 to 10×10-6 g·mL-1 and the limit of detection is 0.02×10-6 g·mL-1 with a relative standard deviation(n=11) of ca.2.4% for 1.0×10-6 g·mL-1 pefloxacin mesylate.The method has been applied to the determination of the studied drug in tablets,injection and biological fliuds successfully.