Leilei Wang, Liwen Zheng, Xue‐Qing Kong
Jan 2, 2017
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Influential Citations
6
Citations
Journal
Green Chemistry Letters and Reviews
Abstract
ABSTRACT We reported a green and simple Cu-catalyzed method for the efficient synthesis of 2-chloro-7-cyclopentyl-N,N-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide as the key intermediate in the synthetic approaches to pyrrolo[2,3-d]pyrimidine derivatives from 5-bromo-2,4-dichloropyrimidine through two routes in four steps and five steps, respectively. This method provided green and economical approaches toward numerous pyrrolo[2,3-d]pyrimidine derivatives. GRAPHICAL ABSTRACT