Zeng Xue-hua
2008
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Journal
China Pharmacy
Abstract
OBJECTIVE:To establish an HPLC method for the determination of cefteram pivoxil content in cefteram pivoxil tablet.METHODS:The chromatography column was C18 with column temperature set at 40 ℃;and the mobile phase consisted of acetonitrile-water(40:60) at a flow rate of 1.2 mL·min-1.The detection wavelength was 235 nm and the sample size was 10 μL.RESULTS:The linear range of cefteram pivoxil was 25~125 μg·mL-1(r=0.999 9,n=7),and the average recovery was 104.98%(RSD=0.86%).CONCLUSION:The method is simple,rapid,accurate and sensitive,and suitable for the quality control of cefteram pivoxil tablet.