M. Nikalje, M. Sasikumar, M. Muthukrishnan
Dec 8, 2010
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Journal
Tetrahedron-asymmetry
Abstract
Abstract A practical and highly efficient enantioselective synthesis of ( R )-phenoxybenzamine hydrochloride has been described for the first time using Jacobsen’s hydrolytic kinetic resolution of a terminal epoxide as a key step and source of chirality.