Yan-Xue Zhang, Ling‐Yan Chen, Jian-Ting Sun
Sep 14, 2020
Citations
0
Influential Citations
14
Citations
Journal
The Journal of organic chemistry
Abstract
A highly efficient gold-catalyzed approach between N,O-acetals and ynamides for the construction of 6-(tert-butyldimethylsilyl)oxy-tetrahydropyrrolo[1,2-c] [1,3]oxazin-1- ones was developed. This reaction tolerated a wide range of substituted N,O-acetals and TsN-substituted ynamides, leading to novel heterocycles in moderate to good yields and with excellent diastereoselectivities (dr > 99:1).